Description
Sodium cyanoborohydride
reagent grade, 95%
Synonym(s):
Sodium cyanotrihydridoborate
About This Item
Linear Formula:
NaBH3CN
CAS Number:
25895-60-7
Molecular Weight:
62.84
Beilstein/REAXYS Number:
4152656
EC Number:
247-317-2
MDL number:
MFCD00003516
UNSPSC Code:
12352306
PubChem Substance ID:
24849595
NACRES:
NA.22
Properties
grade
reagent grade
Quality Level
300
assay
95%
form
powder
reaction suitability
reagent type: reductant
mp
>242 °C (dec.) (lit.)
SMILES string
[Na+].[BH3-]C#N
InChI
1S/CH3BN.Na/c2-1-3;/h2H3;/q-1;+1
InChI key
CVDUGUOQTVTBJH-UHFFFAOYSA-N
General description
Sodium cyanoborohydride, also known as sodium cyanotrihydridoborate, is a mild reducing agent that is stable in acidic conditions. It is widely used in the selective reduction of aryl aldehydes and ketones.[1]
Application
Reagent for selective reductions.[2]
Sodium cyanoborohydride is used as a reagent: 
- To convert the amino-functional Si3N4 surface to a reactive surface with aldehyde groups.[3]
- For coupling amino-modified oligonucleotide probes. [3]
- In the synthesis of a novel phenolate-bridged dilanthanum(III) complex of interest as a model for metalloproteins.
- In the reductive amination of aldehydes[4] and ketones,[5] and in the reductive alkylation of amines.[6]
Safety Information
pictograms
GHS02,GHS06,GHS05,GHS09
signalword
Danger
hcodes
H228,H260,H300 + H310 + H330,H314,H410
pcodes
P210 - P231 + P232 - P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
Hazard Classifications
Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Flam. Sol. 1 - Skin Corr. 1B - Water-react 1
supp_hazards
EUH032
wgk_germany
WGK 3
flash_point_f
closed cup
flash_point_c
closed cup
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges