MilliporeSigma
Sibutramine hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant
- SKU:
- S-011-1ML
On Sale
Description
Sibutramine hydrochloride solution
1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
Synonym(s):
Sibutramine hydrochloride monohydrate, 1-(4-Chlorophenyl)-N,N-dimethyl-alpha-(2-methylpropyl)cyclobutanemethanamine hydrochloride monohydrate, Meridia, Reductil
Empirical Formula (Hill Notation):
C17H26ClN · HCl
CAS Number:
84485-00-7
Molecular Weight:
316.31
EC Number:
200-659-6
MDL number:
MFCD04039806
PubChem Substance ID:
329824413
NACRES:
NA.24
PROPERTIES
grade
certified reference material
Quality Level
300
form
liquid
feature
Snap-N-Spike®/Snap-N-Shoot®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
1.0 mg/mL in methanol (as free base)
technique(s)
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
application(s)
clinical testing
format
single component solution
storage temp.
−20°C
SMILES string
O.Cl.CC(C)CC(N(C)C)C1(CCC1)c2ccc(Cl)cc2
InChI
1S/C17H26ClN.ClH.H2O/c1-13(2)12-16(19(3)4)17(10-5-11-17)14-6-8-15(18)9-7-14;;/h6-9,13,16H,5,10-12H2,1-4H3;1H;1H2
InChI key
KFNNPQDSPLWLCX-UHFFFAOYSA-N
Gene Information
human ... SLC6A2(6530) , SLC6A3(6531) , SLC6A4(6532)
General description
Sibutramine, a SNRI and anorectant, was marketed as a treatment for obesity until 2010 when it was removed from the market over concerns of potential adverse cardiovascular side effects. Sold under trade names Reductil, Meridia®, and Subitrex, this sibutramine Snap-N-Spike® reference solution is applicable for use in LC/MS or GC/MS applications for clinical toxicology and forensic analysis.
Biochem/physiol Actions
Sibutramine is a serotonin and noradrenaline reuptake inhibitor (SNRI). It is an antiobesity drug, which decreases calorie intake and increases energy expanditure. Sibutramine antagonizes MPTP-induced dopamine depletion in mouse brain.
Legal Information
CERILLIANT is a registered trademark of Cerilliant Corporation
Meridia is a registered trademark of Abbott Laboratories Corp.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Cerilliant Corporation
SAFETY INFORMATION
Pictograms
GHS02,GHS06,GHS08
Signal Word
Danger
Hazard Statements
H225 - H301 + H311 + H331 - H370
Precautionary Statements
P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
Target Organs
Eyes
Storage Class Code
3 - Flammable liquids
WGK
WGK 1
Flash Point(F)
49.5 °F - closed cup
Flash Point(C)
9.7 °C - closed cup