Pulegone, 5G

SKU:
CAY-23163-5G
  • $30.00

    • Description

    (R)-(+)-Pulegone

    Product Description

    (R)-(+)-Pulegone is a monoterpene that has been found in a variety of plants, including Labiatae species and M. verticillata, and has anti-inflammatory activity.1 It stimulates proliferation of lymphocytes derived from allergic patients in vitro when used at concentrations of 6.2 and 62 µg/ml and reduces the level of IL-13 in supernatant from lymphocyte cultures when used at a concentration of 62 µg/ml.2 (R)-(+)-Pulegone decreases scratching behavior and reduces skin thickness in a mouse model of atopic dermatitis when administered topically at doses ranging from 0.1 to 10 µM. It also decreases serum IgE levels and skin protein levels of nerve growth factor, IFN-γ, IL-6, IL-1β, TNF-α, NF-κB, phosphorylated ERK1/2, and phosphorylated JNK.

    WARNING This product is not for human or veterinary use.

    Technical Information
    Formal Name
    5R-methyl-2-(1-methylethylidene)-cyclohexanone
    CAS Number
    89-82-7
    Synonyms
    • NSC 15334
    • D-Pulegone
    Molecular Formula
    C10H16O
    Formula Weight
    152.2
    Purity
    ≥95%
    A neat oil
    Solubility
    Chloroform: Soluble
    • Ethanol: Soluble
    SMILES
    O=C(C[C@H](C)CC/1)C1=C(C)\C
    InChi Code
    InChI=1S/C10H16O/c1-7(2)9-5-4-8(3)6-10(9)11/h8H,4-6H2,1-3H3/t8-/m1/s1
    InChi Key
    NZGWDASTMWDZIW-MRVPVSSYSA-N
    Shipping & Storage Information
    Storage
    -20°C
    Shipping
    Room Temperature in continental US; may vary elsewhere
    Stability
    ≥ 4 years