Potassium tert-pentoxide solution, 100ML

SKU:
702757-100ML
  • $299.00

    • Description

    Potassium tert-pentoxide solution

    2 M in THF

    Synonym(s):
    Potassium tert-amylate, Potassium (2-methyl-2-butoxide), Potassium tert-pentylate
    Linear Formula:
    CH3CH2C(CH3)2OK
    CAS Number:
    41233-93-6
    Molecular Weight:
    126.24
    Beilstein:
    4149025
    MDL number:
    MFCD00064808
    PubChem Substance ID:
    329762401
    NACRES:
    NA.22

    PROPERTIES

    form

    liquid

    Quality Level

    100

    concentration

    2 M in THF

    density

    0.920 g/mL at 25 °C

    SMILES string

    [K+].CCC(C)(C)[O-]

    InChI

    1S/C5H11O.K/c1-4-5(2,3)6;/h4H2,1-3H3;/q-1;+1

    InChI key

    ZRLVQFQTCMUIRM-UHFFFAOYSA-N

    General description

    Potassiumtert-pentoxide solution is a strong and sterically hindered alkoxide baseprepared by treating oil-free potassium hydride with anhydrous t-pentylalcohol in anhydrous solvent.

    Application

    Potassium tert-pentoxide solution can be used as a base in the:
    • Wittig reaction of ketoesters with methyltriphenylphosphonium bromide to synthesize alkenes.
    • Palladium-catalyzed Buchwald-Hartwig amination reaction.
    It can also be used:
    • To prepare potassium tert-pentoxide-crown ether complexes, which is used as a Lewis base catalyst in Mukaiyama aldol reaction.
    • As an activator for (difluoromethyl)trimethylsilane to generate difluoromethyl-carbanion which reacts with isothiocyanate to synthesize α, α-difluoromethyl thioamide.

    Features and Benefits

    In the absence of air and moisture, potassium tert-pentoxide solutions in benzene or toluene may be stored in a refrigerator for up to 1 year without significant deterioration.

    SAFETY INFORMATION

    Pictograms

    GHS02,GHS05,GHS07,GHS08

    Signal Word

    Danger

    Hazard Statements

    H225 - H302 - H314 - H335 - H336 - H351

    Precautionary Statements

    P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338

    Hazard Classifications

    Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B

    Supplementary Hazards

    EUH019

    Storage Class Code

    3 - Flammable liquids

    WGK

    WGK 3

    Flash Point(F)

    1.4 °F - Solvent

    Flash Point(C)

    -17 °C - Solvent

    Personal Protective Equipment

    dust mask type N95 (US), Eyeshields, Gloves