Potassium antimonyl tartrate trihydrate ACS reagent, 100G

SKU:
383376-100G
  • $91.90

    • Description

    Potassium antimonyl tartrate trihydrate

    ACS reagent, ≥99%

    Synonym(s):
    Antimony potassium tartrate trihydrate, Tartar emetic
    Empirical Formula (Hill Notation):
    C8H4K2O12Sb2 · 3H2O
    CAS Number:
    28300-74-5
    Molecular Weight:
    667.87
    EC Number:
    234-293-3
    MDL number:
    MFCD00167056
    PubChem Substance ID:
    24863959
    NACRES:
    NA.21

    PROPERTIES

    grade

    ACS reagent

    Quality Level

    200

    Assay

    ≥99%
    99.0-103.0%

    form

    powder

    impurities

    ≤0.020 meq/g Titr. acid or base

    loss

    ≤2.7% loss on drying

    mp

    ≥300 °C (lit.)

    solubility

    water: soluble

    cation traces

    As: ≤0.015%

    SMILES string

    O.O.O.[K+].[K+].O=C1O[Sb-]23OC1C4O[Sb-]5(OC(C(O2)C(=O)O3)C(=O)O5)OC4=O

    InChI

    1S/2C4H4O6.2K.3H2O.2Sb/c2*5-1(3(7)8)2(6)4(9)10;;;;;;;/h2*1-2H,(H,7,8)(H,9,10);;;3*1H2;;/q2*-2;2*+1;;;;2*+3/p-4

    InChI key

    WBTCZEPSIIFINA-UHFFFAOYSA-J

    General description

    Potassium antimonyl tartrate trihydrate is a metalloid salt in which the antimony is in trivalent state (SbIII).[1] Potassium antimonyl tartrate (PAT) is an antiparasitic agent[2] predominantly used for treating infections caused by the parasite Leishmania.[3] Its antiangiogenic and antitumor properties has been investigated in nonsmall-cell lung cancer (NSCLC) cells.[4] Studies in Chinese hamster ovary cells show that it may prevent the repair of DNA double strand breaks (DSBs) caused by γ-irradiation.[5]

    Application

    Potassium antimonyl tartrate trihydrate has been used in the dose-inhibition experiments to evaluate the dose-inhibition curves of antimony-based antileishmanial compoundsagainst Leishmania promastigotes in medium 199.[6]
    Potassium antimonyl tartrate trihydrate may be used to prepare antimony (Sb(III)) stock solution in deionized water (100mg/L).[7] It may also be employed in the spectrophotometric determination of total phosphorus in dry sediments.[8]

    Packaging

    5, 100, 500, 500 g

    SAFETY INFORMATION

    Signal Word

    Danger

    Hazard Statements

    H301 - H315 - H317 - H332 - H411

    Precautionary Statements

    P261 - P273 - P280 - P301 + P310 - P302 + P352 - P304 + P340 + P312

    Hazard Classifications

    Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Aquatic Chronic 2 - Skin Irrit. 2 - Skin Sens. 1

    Storage Class Code

    6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

    WGK

    WGK 3

    Flash Point(F)

    Not applicable

    Flash Point(C)

    Not applicable

    Personal Protective Equipment

    dust mask type N95 (US), Eyeshields, Gloves