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Phloretin, 250MG

SKU:
CAY-14452-250MG
  • $41.00

    • Description

    Phloretin, 250MG

    Technical Information
    Formal Name
    3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanone
    CAS Number
    60-82-2
    Synonyms
    • NSC 407292
    • RJC 02792
    Molecular Formula
    C15H14O5
    Formula Weight
    274.3
    Purity
    ≥98%
    Formulation(Request formulation change)
    A crystalline solid
    Solubility(Learn about Variance in Solubility)
    • DMF: 30 mg/ml
    • DMSO: 30 mg/ml
    • DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
    • Ethanol: 10 mg/ml
    λmax
    225, 287 nm
    SMILES
    OC1=CC=C(CCC(C2=C(O)C=C(O)C=C2O)=O)C=C1
    InChi Code
    InChI=1S/C15H14O5/c16-10-4-1-9(2-5-10)3-6-12(18)15-13(19)7-11(17)8-14(15)20/h1-2,4-5,7-8,16-17,19-20H,3,6H2
    InChi Key
    VGEREEWJJVICBM-UHFFFAOYSA-N
    Shipping & Storage Information
    Storage
    -20°C
    Shipping
    Room Temperature in continental US; may vary elsewhere
    Stability
    ≥ 4 years
    Product Description

    Phloretin is a natural phenol which inhibits a variety of transporters. It inhibits the monocarboxylate transporters MCT1 and MCT2 (IC50 = 28 and 14 µM, respectively), restricting the rapid transport of monocarboxylates like lactate and pyruvate across the plasma membrane.1 Phloretin also blocks the sodium/D-glucose cotransporter (Ki = 86 µM) and the human concentrative nucleoside transporter 3 (Ki = 32 µM).2,3

    WARNING This product is not for human or veterinary use.