Phenolphthalein, ACS reagent, 2.5KG

SKU:
105945-2.5KG
  • $641.00

    • Description

    Phenolphthalein, ACS reagent, 2.5KG

    Synonym(s):
    3,3-Bis(4-hydroxyphenyl)-1(3H)-isobenzofuranone
    Empirical Formula (Hill Notation):
    C20H14O4
    CAS Number:
    77-09-8
    Molecular Weight:
    318.32
    Colour Index Number:
    764
    Beilstein/REAXYS Number:
    284423
    EC Number:
    201-004-7
    MDL number:
    MFCD00005913
    UNSPSC Code:
    12171500
    PubChem Substance ID:
    24846716
    NACRES:
    NA.47

    Properties

    grade

    ACS reagent

    Quality Level

    200

    form

    powder

    technique(s)

    titration: suitable

    visual transition interval

    8.0-10, colorless to red

    mp

    261-263 °C (lit.)

    solubility

    acetone: soluble

    density

    1.27 g/cm3 at 32 °C

    λmax

    374 nm (2nd)
    552 nm

    application(s)

    diagnostic assay manufacturing
    hematology
    histology

    storage temp.

    room temp

    SMILES string

    Oc1ccc(cc1)C2(OC(=O)c3ccccc23)c4ccc(O)cc4

    InChI

    1S/C20H14O4/c21-15-9-5-13(6-10-15)20(14-7-11-16(22)12-8-14)18-4-2-1-3-17(18)19(23)24-20/h1-12,21-22H

    InChI key

    KJFMBFZCATUALV-UHFFFAOYSA-N

    General description

    Phenolphthalein is an indicator for acid-base titration reactions.[1] It changes from colorless to violet-red between pH 8.3-9.8, it is red in extremely acidic solutions, and colorless in extremely alkaline solutions.[2]

    It is present as a nonionic, lipophilic lactone in aqueous neutral solutions. It exists as a hydrophilic dianion in alkaline solutions.

    Application

    Phenolphthalein has been commonly used as an indicator in the fields of biology and medicine. Its applications include:

    • the development of novel technique to monitor the vacuum freeze-drying process[3]
    • the determination of the depth of carbonation in concrete[4]
    • the utilization of liquid marbles to sense gaseous environmental components
    • the estimation of total acidity in vinegar
    • the assessment of sodium hydroxide penetration into potatoes following chemical peeling
    • as a model organic compound in the evaluation of the capture efficiency of various cyclodextrin constructs such as nanofiber-CD

    Biochem/physiol Actions

    Phenolphthalein is colorless in acidic solutions and turns pink in basic solutions.

    Principle

    Phenolphthalein undergoes structural modification when there is a change in pH or in the structural state of water.[1] It is a nonionic, lipophilic colorless lactone in aqueous neutral solutions and a hydrophilic dianion in alkaline solutions.[2]

    Safety Information

    pictograms

    GHS08,GHS07

    signalword

    Danger

    hcodes

    H315,H341,H350,H361f

    pcodes

    P202 - P264 - P280 - P302 + P352 - P308 + P313 - P332 + P313

    Hazard Classifications

    Carc. 1B - Muta. 2 - Repr. 2 - Skin Irrit. 2

    wgk_germany

    WGK 3

    flash_point_f

    Not applicable

    flash_point_c

    Not applicable

    ppe

    Eyeshields, Gloves, type P3 (EN 143) respirator cartridges