Olanzapine solution 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant

SKU:
O-024-1ML
  • $95.50

    • Description

    Olanzapine solution

    1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant

    Empirical Formula (Hill Notation):
    C17H20N4S
    CAS Number:
    132539-06-1
    Molecular Weight:
    312.43
    EC Number:
    200-835-2
    UNSPSC Code:
    41116107
    NACRES:
    NA.24

    PROPERTIES

    grade

    certified reference material

    Quality Level

    300

    form

    liquid

    feature

    Snap-N-Spike®/Snap-N-Shoot®

    packaging

    ampule of 1 mL

    manufacturer/tradename

    Cerilliant®

    concentration

    1.0 mg/mL in acetonitrile

    technique(s)

    gas chromatography (GC): suitable
    liquid chromatography (LC): suitable

    application(s)

    clinical testing

    format

    single component solution

    storage temp.

    −20°C

    SMILES string

    CN1CCN(CC1)C2=Nc3ccccc3Nc4sc(C)cc24

    InChI

    1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3

    InChI key

    KVWDHTXUZHCGIO-UHFFFAOYSA-N

    Gene Information

    human ... DRD2(1813) , DRD3(1814) , DRD4(1815) , HTR2A(3356) , HTR2C(3358)

    DESCRIPTION

    General description

    An analytical reference standard for use in LC/MS or GC/MS applications including clinical toxicology analysis or therapeutic drug monitoring. Marketed under the trade name Zyprexa®, olanzapine is an atypical antipsychotic drug used in the treatment of schizophrenia and bipolar disorder.

    Application

    • Metabolic impact of Olanzapine in bipolar disorder: A network meta-analysis of randomized-controlled trials assessed the metabolic effects of antipsychotics and mood stabilizers, including Olanzapine, in patients with bipolar disorder, providing insights into its pharmacodynamic properties and implications for treatment optimization (Kong et al., 2024).
    • Machine learning in schizophrenia research: Olanzapine′s effectiveness was evaluated through a systematic review employing machine learning to predict violent behaviors in schizophrenia spectrum disorders. This study underscores the relevance of antipsychotic treatment profiling in enhancing patient-specific therapeutic strategies (Delvecchio et al., 2024).
    • Solubility and bioavailability enhancement: Research focused on the evaluation of polymeric matrices for loading poorly water-soluble drugs, like Olanzapine, into mesoporous silica. This study advances the development of more effective and bioavailable oral liquid formulations of Olanzapine (Barmpalexis et al., 2024).

    Legal Information

    CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
    Snap-N-Shoot is a registered trademark of Cerilliant Corporation
    Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
    Zyprexa is a registered trademark of Eli Lilly and Co.

    SAFETY INFORMATION

    signalword

    Danger

    hcodes

    H225,H302 + H312 + H332,H319

    pcodes

    P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338

    Hazard Classifications

    Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

    wgk_germany

    WGK 2

    flash_point_f

    35.6 °F

    flash_point_c

    2 °C