Nuciferine, 5mg

SKU:
SML2230-5MG
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    • Description

    Nuciferine, 5mg

    ≥98% (HPLC)

    Synonym(s):
    (-)-Nuciferine, (6aR)-5,6,6a,7-Tetrahydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline, (R)-1,2-Dimethoxyaporphine, (R)-Nuciferine, 1,2-Dimethoxy-6a-aporphine, D-(-)-Nuciferine, Nuciferin, Sanjoinine E, 1,2-Dimethoxy 6aβ-aporphine
    Empirical Formula (Hill Notation):
    C19H21NO2
    CAS Number:
    475-83-2
    Molecular Weight:
    295.38
    MDL number:
    MFCD01664592
    NACRES:
    NA.77

    PROPERTIES

    biological source

    Nelumbo nucifera

    Assay

    ≥98% (HPLC)

    form

    powder

    optical activity

    [α]/D -145 to -165°, c = 0.5 in ethanol

    color

    white to beige

    solubility

    DMSO: 2 mg/mL, clear (warmed)

    storage temp.

    2-8°C

    SMILES string

    [H][C@]1(C2=C3C(OC)=C(OC)C=C2CCN1C)CC4=C3C=CC=C4

    InChI

    1S/C19H21NO2/c1-20-9-8-13-11-16(21-2)19(22-3)18-14-7-5-4-6-12(14)10-15(20)17(13)18/h4-7,11,15H,8-10H2,1-3H3/t15-/m1/s1

    InChI key

    ORJVQPIHKOARKV-OAHLLOKOSA-N

    DESCRIPTION

    Biochem/physiol Actions

    Nuciferine is a major active component from lotus leaf that produces antipsychotic-like effect in rodents. Nuciferine is a potent inverse agonist at human 5-HT7 receptor. Nuciferine attenuates fructose-induced hyperuricemia, dyslipidemia and systemic inflammation in rats.

    SAFETY INFORMATION

    Signal Word

    Danger

    Hazard Statements

    H301

    Precautionary Statements

    P264 - P270 - P301 + P310 - P405 - P501

    Hazard Classifications

    Acute Tox. 3 Oral

    Storage Class Code

    6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

    WGK

    WGK 3

    Flash Point(F)

    Not applicable

    Flash Point(C)

    Not applicable