Description
Noladin ether ≥98% (HPLC), 5MG
Synonym(s):
2-Arachidonylglyceryl ether, 2-[(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraen-1-yloxy]-1,3-propanediol; 2-AG ether, HU 310
Empirical Formula (Hill Notation):
C23H40O3
CAS Number:
222723-55-9
Molecular Weight:
364.56
EC Number:
200-578-6
Quality Level
100
assay
≥98% (HPLC)
form
ethanol solution (10 mg/mL (1% w/v))
drug control
regulated under CDSA - not available from Sigma-Aldrich Canada
color
colorless to light yellow
shipped in
dry ice
storage temp.
−70°C
InChI
1S/C23H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-26-23(21-24)22-25/h6-7,9-10,12-13,15-16,23-25H,2-5,8,11,14,17-22H2,1H3/b7-6-,10-9-,13-12-,16-15-
InChI key
CUJUUWXZAQHCNC-DOFZRALJSA-N
Packaging
5, 25 mg in glass bottle
Biochem/physiol Actions
Noladin ether (2-Arachidonyl glycerol ether) is a stable analog of the endogenous cannabanoid 2-Arachidonylglycerol (2-AG) with selectivity for CB1 receptors. Noladin ether is a CB1 agonist. The Ki values for CB1 vs CB2 receptors are 21.2 nM and 3 mM, respectively. Noladin ether induces sedation and has modest antinociceptive activity in vivo, and reduces inter ocular pressure after administration in the eye.
Pictograms
GHS02,GHS07
Signal Word
Danger
Hazard Statements
H225 - H319
Precautionary Statements
P210 - P305 + P351 + P338
RIDADR
UN1170 - class 3 - PG 2 - Ethanol, solution
WGK Germany
WGK 2
Flash Point(F)
57.2 °F - closed cup
Flash Point(C)
14.0 °C - closed cup
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