Niacinamide, 1G, Pharmaceutical Secondary Standard; Certified Reference Material

SKU:
PHR1033-1G
  • $99.40

    • Description

    Niacinamide, 1G

    Pharmaceutical Secondary Standard; Certified Reference Material

    Synonym(s):
    Niacinamide, Vitamin PP, Nicotinic acid amide, Vitamin B3, Pyridine-3-carboxylic acid amide, Nicotinamide
    Empirical Formula (Hill Notation):
    C6H6N2O
    CAS Number:
    98-92-0
    Molecular Weight:
    122.12
    Beilstein:
    383619
    EC Number:
    202-713-4
    MDL number:
    MFCD00006395
    PubChem Substance ID:
    329823063

    PROPERTIES

    Quality Level

    300

    grade

    certified reference material
    pharmaceutical secondary standard

    Agency

    traceable to BP 460
    traceable to Ph. Eur. N0600000
    traceable to USP 1462006

    CofA

    current certificate can be downloaded

    technique(s)

    HPLC: suitable
    gas chromatography (GC): suitable

    mp

    128-131 °C (lit.)

    application(s)

    pharmaceutical (small molecule)

    format

    neat

    storage temp.

    2-30°C

    SMILES string

    NC(=O)c1cccnc1

    InChI

    1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)

    InChI key

    DFPAKSUCGFBDDF-UHFFFAOYSA-N

    General description

    Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

    Application

    These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
    Niacinamide may be used as a pharmaceutical reference standard for the determination of the analyte in plasma, pharmaceutical formulations and infant/Adult nutritional formula powder by various chromatography methods.

    Biochem/physiol Actions

    Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor
    Niacinamide/Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor

    Analysis Note

    These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

    Other Notes

    This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

    SAFETY INFORMATION

    Signal Word

    Warning

    Hazard Statements

    H319

    Precautionary Statements

    P264 - P280 - P305 + P351 + P338 - P337 + P313

    Hazard Classifications

    Eye Irrit. 2

    Storage Class Code

    11 - Combustible Solids

    WGK

    WGK 1

    Flash Point(F)

    302.0 °F - closed cup

    Flash Point(C)

    150 °C - closed cup