Description
Nalmefene Hydrochloride
≥98% (HPLC)
Synonym(s):
(5a)-17-(Cyclopropylmethyl)-4,5-epoxy-6-methylene-morphinan-3,14-diol hydrochloride, NIH 1036, Nalmefene HCl
Empirical Formula (Hill Notation):
C21H25NO3·HCl
CAS Number:
58895-64-0
Molecular Weight:
375.89
MDL number:
MFCD27937056
PROPERTIES
Quality Level
100
Assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
C=C1CC[C@@]2(O)[C@H]3CC4=C5[C@@]2(CCN3CC6CC6)[C@H]1OC5=C(C=C4)O.Cl
InChI
1S/C21H25NO3.ClH/c1-12-6-7-21(24)16-10-14-4-5-15(23)18-17(14)20(21,19(12)25-18)8-9-22(16)11-13-2-3-13;/h4-5,13,16,19,23-24H,1-3,6-11H2;1H/t16-,19+,20+,21-;/m1./s1
InChI key
GYWMRGWFQPSQLK-OPHZJPRHSA-N
DESCRIPTION
Biochem/physiol Actions
Nalmefene hydrochloride, a naltrexone analogue, is an inverse agonist at the μ-opioid receptor (MOR) and as a weak partial agonist at the κ-opioid receptor. Nalmefene hydrochloride is used as treatment for addiction.
SAFETY INFORMATION
Signal Word
Danger
Hazard Statements
H301 - H336 - H410
Precautionary Statements
P261 - P264 - P270 - P271 - P273 - P301 + P310
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Chronic 1 - STOT SE 3
Target Organs
Central nervous system
Storage Class Code
6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable