N-Desmethylcyclobenzaprine hydrochloride solution, 1.0mg/mL in methanol (as free base), ampule of 1mL, certified reference material, Cerilliant

SKU:
D-088-1ML
  • $166.00

    • Description

    N-Desmethylcyclobenzaprine hydrochloride solution 

    1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

    Empirical Formula (Hill Notation):
    C19H19N · HCl
    CAS Number:
    438-59-5
    Molecular Weight:
    297.82
    MDL number:
    MFCD01731061
    UNSPSC Code:
    41116107
    PubChem Substance ID:
    329798646
    NACRES:
    NA.24

    Properties

    grade

    certified reference material

    Quality Level

    300

    form

    liquid

    feature

    (Snap-N-Spike®)

    packaging

    ampule of 1 mL

    manufacturer/tradename

    Cerilliant®

    concentration

    1.0 mg/mL in methanol (as free base)

    technique(s)

    gas chromatography (GC): suitable
    liquid chromatography (LC): suitable

    application(s)

    clinical testing

    format

    single component solution

    storage temp.

    −20°C

    SMILES string

    CNCCC=C1C2=C(C=CC=C2)C=CC3=C1C=CC=C3.Cl

    InChI

    1S/C19H19N.ClH/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19;/h2-5,7-13,20H,6,14H2,1H3;1H

    InChI key

    UZMPCPFDZYTEJG-UHFFFAOYSA-N

    Description

    General description

    A certified Snap-N-Spike® Solution suitable for cyclobenzaprine testing methods by GC/MS or LC/MS for applications in pain prescription monitoring, forensic analysis, urine drug testing, or clinical toxicology. Also known as norcyclobenzaprine, N-desmethylcyclobenzaprine is the major urinary metabolite of the skeletal muscle relaxant cyclobenzaprine. Cyclobenzaprine, sold under trade names Flexeril®, Fexmid®, and Amrix®, is used to relieve skeletal muscle spasms and associated pain from acute musculoskeletal conditions.

    Application


      • Formation of Mammalian Metabolites of Cyclobenzaprine: Research demonstrated that the fungus Cunninghamella elegans could produce mammalian metabolites of cyclobenzaprine, including N-Desmethylcyclobenzaprine. This study highlights the potential use of microbial models in pharmacokinetic studies to simulate and study drug metabolism pathways, providing a cost-effective and simpler alternative to traditional in vivo metabolic studies (Zhang et al., 1996).

    Legal Information

    Amrix is a registered trademark of Ivax International GMBH LLC
    CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
    Fexmid is a registered trademark of Shionogi Inc.
    Flexeril is a registered trademark of ALZA Corporation
    Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

    Safety Information

    signalword

    Danger

    hcodes

    H225,H301 + H311 + H331,H370,H411

    pcodes

    P210 - P273 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311

    Hazard Classifications

    Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Flam. Liq. 2 - STOT SE 1

    target_organs

    Eyes

    wgk_germany

    WGK 1