Methiocarb-d₃ is intended for use as an internal standard for the quantification of methiocarb (Item No. 25627) by GC- or LC-MS. Methiocarb is a carbamate pesticide with insecticidal, molluscicidal, acaricidal, and bird repellant properties.^1,2,3,4,5 It inhibits acetylcholinesterase (AChE) activity and is toxic to the western flower thrip (F. occidentalis; IC₅₀ = 2.1 μM; LC₅₀ = 3.26 ppm).² Methiocarb is also toxic to the land snail M. obstructa (LD₅₀ = 27.4 μg/snail) and the citrus mite A. pelekassi, inducing 94% mortality when used at a concentration of 0.5 ppm.^1,3 It reduces the seasonal percentages of cotton bolls infested with pink bollworm (P. gossypiella) to 4%, compared with 65% infestation in untreated controls, when applied to cotton fields at a concentration of 1.86 lb/acre.⁵ Methiocarb reduces damage to grapes by song birds when applied to vineyards at a concentration of 2.5 lbs AI per 100 gal water per acre.⁴ It is an estrogen receptor α (ERα) and ERβ agonist (EC₂₀s = 19.87 and 20.24 μM, respectively) and an androgen receptor antagonist (IC₅₀ = 13.89 μM) in cell-based reporter assays.⁶ It is toxic to juvenile rainbow trout (O. mykiss) and guppies (P. reticulata) with LC₅₀ values of 0.8 and 1.48 mg/L, respectively, at 48 hours of exposure.⁷ Formulations containing methiocarb have been used in the agricultural control of pests.

WARNING This product is not for human or veterinary use.

This product is sold exclusively for research and analytical uses. It is formulated and packaged for use in controlled laboratory settings. Bulk sizes are not available for purchase.