Methanol, HPLC grade, 4L

SKU:
1060184000
  • $256.00

    • Description

    Methanol, for liquid chromatography LiChrosolv®

    Synonym(s):
    MeOH, Hydroxymethane, Carbinol, Methyl alcohol
    Linear Formula:
    CH3OH
    CAS Number:
    67-56-1
    Molecular Weight:
    32.04
    Beilstein/REAXYS Number:
    1098229
    MDL number:
    MFCD00004595
    EC Index Number:
    200-659-6

    PROPERTIES

    grade

    HPLC grade
    isocratic

    Quality Level

    100

    vapor density

    1.11 (vs air)

    vapor pressure

    128 hPa ( 20 °C)
    410 mmHg ( 50 °C)
    97.68 mmHg ( 20 °C)

    product line

    LiChrosolv®

    assay

    ≥99.8% (GC)

    form

    liquid

    autoignition temp.

    725 °F

    potency

    5628 mg/kg LD50, oral (Rat)
    17100 mg/kg LD50, skin (Rabbit)

    expl. lim.

    36 %

    technique(s)

    HPLC: suitable

    impurities

    ≤0.0002 meq/g Acidity
    ≤0.0002 meq/g Alkalinity
    ≤0.03% Water

    evapn. residue

    ≤3.0 mg/L

    color

    APHA: ≤10

    transmittance

    225 nm, ≥50%
    240 nm, ≥80%
    265 nm, ≥98%

    refractive index

    n20/D 1.329 (lit.)

    kinematic viscosity

    0.54-0.59 cSt(20 °C)

    bp

    64.7 °C (lit.)

    mp

    −98 °C (lit.)

    transition temp

    flash point 9.7 °C

    density

    0.791 g/mL at 25 °C (lit.)

    format

    neat

    storage temp.

    2-30°C

    SMILES string

    CO

    InChI

    1S/CH4O/c1-2/h2H,1H3

    InChI key

    OKKJLVBELUTLKV-UHFFFAOYSA-N

    General description

    LiChrosolv® solvents exhibit high degree of UV transmittance, low particle count, low acidity and alkalinity and low evaporation residue level. This makes them ideal for reproducible separations.

    Application

    Intended for HPLC and UHPLC-MS applications.
    Featured in method development of:
    • Benazepril - USP Method Benazepril RS
    • Betamethasone - USP Method Betamethasone Valerate Assay
    • Irbesartan - USP Method Irbesartan Assay
    • Lamivudine - USP Method Lamivudine RS
    • Lansoprazole - USP Method Lansoprazole RS
    • Levofloxacin - USP Method Levofloxacin RS - USP Method Levofloxacin Assay
    • Nifedipine - USP Method Nifedipine RS - USP Method Nifedipine Assay
    • Pharmacopoeia Monograph Methods - HPLC and UHPLC methods for Regulated Drug Analysis
    • Pioglitazone - USP Method Pioglitazone HCl RS - USP Method Pioglitazone HCl Assay

    Features and Benefits

    • suitability tested and specified for UHPLC-MS and UHPLC-UV: for analytical flexibility
    • specified quality in positive and negative in positive and negative electrospray ionization (ESI) and atmospheric-pressure chemical ionization-mass spectrometry (APCI-MS) for lowest detection limits and confidence in analyses for all important MS modes (test 1)
      —ESI/APCI (+) < 2 ppb
      —ESI/APCI (-) < 10 ppb
    • lowest impurity profile: for interference-free baselines (test 2)
    • microfiltered through 0.2 μm filter (test 3) to provide:
      —A long lifespan to filters and mechanical parts of HPLC systems
      ––reduced risk of column clogging
    • packaged in borosilicate glass bottles for minimized metal ion contaminations
    • lowest levels of trace metal impurities for a minimum metal ion adduct formation
      —<5 ppb
    • lowest level of polyethylene glycol (PEG) impurities in UHPLC-MS solvent lineup (PEG S/N signal-to-noise-ratio < 50)

    Preparation Note

    Product filtered through a 0.2 μm filter

    Analysis Note

    Evaporation Number: 1.9
    Purity (GC): ≥ 99.8 %
    Identity (IR): conforms
    Evaporation residue: ≤ 3.0 mg/l
    Water: ≤ 0.03 %
    Color: ≤ 10 Hazen
    Acidity: ≤ 0.0002 meq/g
    Alkalinity: ≤ 0.0002 meq/g
    Transmission (at 225 nm): ≥ 50 %
    Transmission (at 240 nm): ≥ 80 %
    Transmission (from 265 nm): ≥ 98 %
    Filtered by 0.2 µm filter

    Other Notes

    Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

    Legal Information

    LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

    SAFETY INFORMATION

    pictograms

    GHS02,GHS06,GHS08

    signalword

    Danger

    hcodes

    H225 - H301 + H311 + H331 - H370

    pcodes

    P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311

    Hazard Classifications

    Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

    Storage Class

    3 - Flammable liquids

    wgk_germany

    WGK 2

    flash_point_f

    49.5 °F - closed cup

    flash_point_c

    9.7 °C - closed cup