Description
L-Tryptophan, 100G
L-Tryptophan is an essential amino acid.1 It serves as a substrate for tryptophan hydroxylase (TPH), indoleamine-2,3-dioxygenase (IDO), and tryptophan-2,3-dioxygenase (TDO) for the biosynthesis of serotonin (5-HT; Item No. 14332) and kynurenine (Item No. 11305).2 L-Tryptophan is also metabolized by enteric bacteria expressing tryptophanase into indole, pyruvate, and ammonia.3 It increases 5-HT, 5-hydroxy-L-tryptophan (5-HTP; Item No. 20539), and 5-hydroxyindolacetic acid (5-HIAA; Item No. 22889) levels in the diencephalon of rats when administered at a dose of 300 mg/kg.4 L-Tryptophan decreases immobility time in the forced swim test in rats when administered at doses of 4 and 20 mg/kg per day for eight weeks.5
WARNING This product is not for human or veterinary use.
Technical Information
- NSC 13119
- (–)-Tryptophan
- PBS (pH 7.2): 1 mg/ml