Description
PHR1004 Supelco
Ibuprofen
Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: α-Methyl-4-(isobutyl)phenylacetic acid, (±)-2-(4-Isobutylphenyl)propanoic acid
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CAS Number 15687-27-1
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Empirical Formula (Hill Notation) C13H18O2
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Molecular Weight 206.28
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EC Number 239-784-6
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MDL number MFCD00010393
Description
General description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Application
Ibuprofen may be used as a standard in the quantitative determination of ibuprofen in samples of human plasma using high performance liquid chromatography (HPLC).[1] It may also be used as a reference standard in the determination of ibuprofen in dog plasma using liquid chromatography (LC).[2]
Biochem/physiol Actions
Cyclooxygenase (COX) inhibitor that has greater activity against COX-1 than against COX-2.
Cyclooxygenase (COX) inhibitor that has greater activity against COX-1 than against COX-2.
Analysis Note
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Other Notes
This product was designed, produced and verified for accuracy and stability in accordance with ISO/IEC 17025:2005 (AClass Cert AT-1467), ISO GUIDES 34:2009 (AClass Cert AR-1470).
Properties
Related Categories | Additional Standards, Analytical Standards,Analytical/Chromatography, Chromatography, Drugs & Metabolites, More... |
grade | certified reference material |
- | pharmaceutical secondary standard |
InChI Key | HEFNNWSXXWATRW-UHFFFAOYSA-N |
form | neat |
Featured Industry | Pharmaceutical (small molecule) |
format | neat |
pharmacopeia traceability | traceable to BP 539 |
- | traceable to PhEur I0020000 |
- | traceable to USP 1335508 |