Ganoderenic Acid A

SKU:
CAY-27685-1MG
  • $93.00

    • Description

    Ganoderenic Acid A

    Ganoderenic acid A is a triterpenoid originally isolated from G. lucidum that has enzyme inhibitory activities.1,2,3 It is an inhibitor of β-glucuronidase (IC50 = 0.12 mg/ml in rat liver microsomes).2 Ganoderenic acid A (100 mg/kg) reduces increases in serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) in a rat model of liver injury induced by carbon tetrachloride (CCl4). It also inhibits aldose reductase by 54.2% when used at a concentration of 100 µg/ml.3

    WARNING This product is not for human or veterinary use.

    Technical Information
    Formal Name
    (7β,15α,20E)-7,15-dihydroxy-3,11,23-trioxo-lanosta-8,20(22)-dien-26-oic acid
    CAS Number
    100665-40-5
    Molecular Formula
    C30H42O7
    Formula Weight
    514.7
    Purity
    ≥98%
    Formulation(Request formulation change)
    A crystalline solid
    Solubility(Learn about Variance in Solubility)
    • DMSO: soluble
    λmax
    247 nm
    SMILES
    CC12C(C[C@H](O)C(C([C@@H](O)CC3/C(C)=C\C(CC(C)C(O)=O)=O)(C)C3(C)C4)=C2C4=O)C(C)(C)C(CC1)=O
    InChi Code
    InChI=1S/C30H42O7/c1-15(10-17(31)11-16(2)26(36)37)18-12-23(35)30(7)25-19(32)13-21-27(3,4)22(34)8-9-28(21,5)24(25)20(33)14-29(18,30)6/h10,16,18-19,21,23,32,35H,8-9,11-14H2,1-7H3,(H,36,37)/b15-10-/t16?,18?,19-,21?,23-,28?,29?,30?/m0/s1
    InChi Key
    OVUOUFPIPZJGME-WHWWCJHXSA-N
    Origin
    Fungi/Ganoderma lucidum
    Shipping & Storage Information
    Storage
    -20°C
    Shipping
    Room Temperature in continental US; may vary elsewhere
    Stability
    ≥ 4 years