Description
Fipronil- 13C2,15N2
Fipronil-13C2,15N2 is intended for use as an internal standard for the quantification of fipronil (Item No. 24128) by GC- or LC-MS. Fipronil is an insecticide that acts as a selective antagonist of insect GABA receptors (IC50s = 28 and 1,660 nM for cockroach and rat receptors, respectively).1 It also inhibits desensitizing and non-desensitizing glutamate-induced chloride currents in cockroach neurons (IC50s = 800 and 10 nM, respectively). Fipronil induces activity of the cytochrome P450 (CYP) isoforms CYP1A1/2, CYP2B1/2, and CYP3A1/2 in isolated rat liver microsomes.2 Formulations containing fipronil have been used as insecticides in veterinary care.
WARNING This product is not for human or veterinary use.
This product is sold exclusively for research and analytical uses. It is formulated and packaged for use in controlled laboratory settings. Bulk sizes are not available for purchase.
echnical Information
- DMSO: sparingly soluble
- Methanol: slightly soluble