Ethylenediaminetetraacetic acid BioUltra, anhydrous

SKU:
EDS-500G
  • $91.20

    • Description

    Ethylenediaminetetraacetic acid

    BioUltra, anhydrous, ≥99% (titration)

    Synonym: (Ethylenedinitrilo)tetraacetic acid, EDTA, Edathamil, Ethylenedinitrilotetraacetic acid

    • CAS Number 60-00-4

       

    • Linear Formula (HO2CCH2)2NCH2CH2N(CH2CO2H)2

       

    • Molecular Weight 292.24

       

    •  Beilstein/REAXYS Number 1716295

       

    •  EC Number 200-449-4

       

    •  MDL number MFCD00003541

       

    •  eCl@ss 39030907

       

    •  PubChem Substance ID 24894713

       

    •  NACRES NA.77

    Properties

    Related Categories Antioxidants and Reducing Agents for Protein Stabilization, Biochemicals and Reagents, Biological Buffers, Buffers A to Z, Calcium Signaling Research Tools,
    Cell Biology, Cell Signaling and Neuroscience, Chelators, Core Bioreagents, Enzyme Inhibitors, Essential Chemicals, Ethylenediaminetetraacetic acid (EDTA) and EDTA Solutions, Intracellular Calcium Signaling, Metal binding chelators, Proteins and Derivatives, Reagents for Protein Stabilization, Research Essentials
    Quality Level 200
    grade anhydrous
    product line BioUltra
    assay ≥99% (titration)
    form powder
    mp 250 °C (dec.) (lit.)
    solubility water: soluble 0.4 g/L at 20 °C
    SMILES string OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O
    InChI 1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)
    InChI key KCXVZYZYPLLWCC-UHFFFAOYSA-N

    General description

    Ethylenediaminetetraacetic acid (EDTA) is a substituted diamine and a versatile compound in household with industrial applications. EDTA chelates metal divalent cations like calcium, magnesium, zinc, copper, manganese by forming metal-EDTA complexes. It finds its application in cleaning products and detergent formulations. In paper and pulp industries, EDTA reduces the adverse effect of metal ions on bleaching. It functions as an antibacterial agent by removing calcium and magnesium divalent cations from the outer membrane and causes loss of lipopolysaccharide from the membrane, making the bacteria susceptible to bactericidal agents. Free EDTA has adverse effect on reproduction and development in mammals.[1] EDTA can chelate ions from deposits that contribute to atherosclerosis, cancers and heart diseases. It can help to overcome cell membrane injury by reducing radical reactions and oxidation processes. It binds to calcium and reduces the risk of hypercalcinemia in cancer patients. Transmembrane ammonium EDTA gradient method aids in drug delivery, increasing drug retention and efficacy of therapeutics and lowers the cytotoxicity levels.[2]

    Application

    EDTA has been used:
    • as a medium supplement in embryo culture using synthetic oviduct fluid culture 1 (SOFC1) medium[3]
    • in incubation of EpCAM+ cells with fluorescein isothiocyanate (FITC) conjugated antibody for cell sorting analysis[4]
    • in pre-treatment of single cell suspension of dendritic cells from spleen for cell sorting with magnetic beads[5]

    Packaging

    1 kg in poly bottle

    100, 500 g in poly bottle