Ergothioneine, 5MG

SKU:
CAY-14905-5MG
  • $62.00

    • Description

    L-(+)-Ergothioneine, 5MG

    Technical Information
    Formal Name
    (αS)-α-carboxy-2,3-dihydro-N,N,N-trimethyl-2-thioxo-1H-imidazole-4-ethanaminium, inner salt
    CAS Number
    497-30-3
    Synonyms
    • 2-Mercaotohistidine Betaine
    • NSC 7175
    Molecular Formula
    C9H15N3O2S
    Formula Weight
    229.3
    Purity
    ≥98%
    Formulation(Request formulation change)
    A crystalline solid
    Solubility
    • PBS (pH 7.2): 10 mg/ml
    λmax
    218, 265 nm
    SMILES
    C[N+](C)([C@@H](CC(N1)=CNC1=S)C([O-])=O)C
    InChi Code
    InChI=1S/C9H15N3O2S/c1-12(2,3)7(8(13)14)4-6-5-10-9(15)11-6/h5,7H,4H2,1-3H3,(H2-,10,11,13,14,15)/t7-/m0/s1
    InChi Key
    SSISHJJTAXXQAX-ZETCQYMHSA-N
    Shipping & Storage Information
    Storage
    -20°C
    Shipping
    Room Temperature in continental US; may vary elsewhere
    Stability
    ≥ 4 years
    Product Description

    L-(+)-Ergothioneine is a naturally-occurring amino acid derived from histidine via hercynine.1 Ergothioneine is a stable antioxidant that scavenges and detoxifies free radicals and oxidants, increases intracellular thiol levels, controls nuclear factor-κB activation, and inhibits inflammatory gene expression.2,3 In addition, it inhibits the peroxynitrite-dependent nitration of nitrotyrosine, blocks oxidative DNA damage and cell death, and prevents the formation of xanthine and hypoxanthine.2,4,5 Ergothioneine is transported by the organic cation/carnitine transporter 1, which has been linked with autoimmune diseases, including rheumatoid arthritis and Crohn’s disease.6

    WARNING This product is not for human or veterinary use.

    Technical Support & Resources

    Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ.