Doramectin, 10MG, Item No. 19467

SKU:
CAY-19467-10MG
  • $198.00

    • Description

    Doramectin

    Item No. 19467

    Technical Information
    Formal Name
    25-cyclohexyl-5-O-demethyl-25-de(1-methylpropyl)-avermectin A1a
    CAS Number
    117704-25-3
    Synonyms
    • Cyclohexylavermectin B1
    • UK 67994
    Molecular Formula
    C50H74O14
    Formula Weight
    899.1
    Purity
    ≥98%
    Formulation
    A crystalline solid
    Solubility
    • Chloroform: Soluble
    • Methanol: Soluble
    • Water: Miscible
    λmax
    245 nm
    SMILES
    C/C([C@@H](O[C@@]1([H])C[C@H](OC)[C@@H](O[C@]2([H])O[C@@H](C)[C@H](O)[C@@H](OC)C2)[C@H](C)O1)[C@@H](C)/C=C/C=C(CO3)/[C@@]([C@@]3([H])[C@H](O)C(C)=C4)(O)[C@]4([H])C5=O)=C\C[C@]6([H])C[C@@](O5)([H])C[C@]7(C=C[C@H](C)[C@@H](C8CCCCC8)O7)O6
    InChi Code
    InChI=1S/C50H74O14/c1-27-13-12-16-34-26-57-47-42(51)30(4)21-37(50(34,47)54)48(53)60-36-22-35(63-49(25-36)20-19-29(3)45(64-49)33-14-10-9-11-15-33)18-17-28(2)44(27)61-41-24-39(56-8)46(32(6)59-41)62-40-23-38(55-7)43(52)31(5)58-40/h12-13,16-17,19-21,27,2
    InChi Key
    QLFZZSKTJWDQOS-YDBLARSUSA-N
    Shipping & Storage Information
    Storage
    -20°C
    Shipping
    Room Temperature in continental US; may vary elsewhere
    Stability
    ≥ 4 years
    Product Description

    Doramectin is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes.1,2 At 0.001 µg/ml, doramectin is fully effective at inhibiting growth in an H. contortus larval development assay.2

    WARNING This product is not for human or veterinary use.