Dimethoate-d₆

Dimethoate-d₆ is intended for use as an internal standard for the quantification of dimethoate (Item No. 24246) by GC- or LC-MS. Dimethoate is an organophosphate pesticide.¹ It is acaricidal against Kanzawa spider mites (LC₅₀ = 7 ppm in an aqueous suspension). Dimethoate (50-200 μM) reduces motility and viability and induces abnormal morphology of rat sperm.² It also increases production of malondialdehyde (MDA) and reduces superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPX) activities in rat epididymal sperm. In vivo, dimethoate (28 mg/kg per day) decreases sperm count, motility, and viability and increases the percentage of morphologically abnormal sperm in rats.³ Dimethoate also induces formation of carcinomas in the adrenal, thyroid, and pituitary glands of male and female rats as well as testicular atrophy, chronic renal disease, polyarteritis, and parathyroid hyperplasia in male rats.⁴ Formulations containing dimethoate have been used as insecticides and miticides in aquatic food production and agriculture.

WARNING This product is not for human or veterinary use.

This product is sold exclusively for research and analytical uses. It is formulated and packaged for use in controlled laboratory settings. Bulk sizes are not available for purchase.