Description
Dichlorvos-d6
Dichlorvos-d6 is intended for use as an internal standard for the quantification of dichlorvos (Item No. 23727) by GC- or LC-MS. Dichlorvos is an organophosphate insecticide and inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE; IC50s = 269 and 44 nM, respectively).1 It also binds to the M2 muscarinic receptor in rat heart homogenates.2 Dichlorvos is lethal to 4-week old German cockroach (B. germanica) nymphs (LD50 = 0.108 μg per insect) and silkworms (B. mori) in third instar (LC50 = 6.63 mg/L) after 24 hours.3,4 It is lethal to zebrafish (D. rerio) embryos (LC50 = 39.75 mg/L after 24 hours) and decreases swimming activity of larvae 6 days after fertilization when administered at a concentration of 25 mg/L in tank water.5 Dichlorvos (150 ppm for 80 weeks) also increases the incidence of benign and malignant neoplasms in male rats from 47 to 88% as compared to controls.6 Formulations containing dichlorvos have been used in the control of insects in residential areas.
WARNING This product is not for human or veterinary use.
Technical Information
- DDVP-d6
- Dichlorovinyl Dimethyl Phosphate-d6
- Methanol: soluble