Daminozide, 100 MG

SKU:
CAY-12033-100MG
  • $26.00

    • Description

    Daminozide, 100MG

    Daminozide is an inhibitor of the 2-oxoglutarate histone lysine demethylases KDM2A, PHF8, and KDM7A (IC50s = 1.5, 0.55, and 2.1 µM, respectively) and a plant growth regulator.1 It is selective for KDM2A, PHF8, and KDM7A over KDM3-6 (IC50s = >100 µM for all), as well as the additional 2-oxoglutarate oxygenases FIH, EGLN1, and BBOX1 (IC50s = >100 µM for all). It reduces peduncle and internodal elongation in C. officinalis when applied at the visible bud stage at concentrations of 1,500, 3,500, or 5,000 ppm.2 Formulations containing daminozide have previously been used in agricultural applications to control plant growth and fruit size.

    WARNING This product is not for human or veterinary use.

    This product is sold exclusively for research and analytical uses. It is formulated and packaged for use in controlled laboratory settings. Bulk sizes are not available for purchase.

    Technical Information
    Formal Name
    1-(2,2-dimethylhydrazide)-butanedioic acid
    CAS Number
    1596-84-5
    Synonyms
    • Aminozide
    Molecular Formula
    C6H12N2O3
    Formula Weight
    160.2
    Purity
    ≥95%
    Formulation(Request formulation change)
    A crystalline solid
    Solubility(Learn about Variance in Solubility)
    • DMF: 5 mg/ml
    • DMSO: 11 mg/ml
    • PBS (pH 7.2): 2 mg/ml
    SMILES
    OC(CCC(NN(C)C)=O)=O
    InChi Code
    InChI=1S/C6H12N2O3/c1-8(2)7-5(9)3-4-6(10)11/h3-4H2,1-2H3,(H,7,9)(H,10,11)
    InChi Key
    NOQGZXFMHARMLW-UHFFFAOYSA-N
    Origin
    Synthetic
    Shipping & Storage Information
    Storage
    -20°C
    Shipping
    Room Temperature in continental US; may vary elsewhere
    Stability
    ≥ 4 years