CP-55940 (HPLC), powder, 10MG

SKU:
C1112-10MG
  • $309.00

    • Description

    CP-55940 >98% (HPLC), powder, 10MG

    Synonym(s):
    5-(1,1-Dimethylheptyl)-2-[5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]phenol
    Empirical Formula (Hill Notation):
    C24H40O3
    CAS Number:
    83002-04-4
    Molecular Weight:
    376.57
    MDL number:
    MFCD00673965
    PubChem Substance ID:
    24278295
    NACRES:
    NA.77

    Quality Level

    100

    assay

    >98% (HPLC)

    form

    powder

    optical activity

    [α]/D -24 to -30°, c = 0.2 in chloroform-d

    drug control

    regulated under CDSA - not available from Sigma-Aldrich Canada

    storage condition

    desiccated

    solubility

    DMSO: 15 mg/mL
    H2O: slightly soluble

    originator

    Pfizer

    storage temp.

    2-8°C

    SMILES string

    CCCCCCC(C)(C)c1ccc([C@@H]2C[C@H](O)CC[C@H]2CCCO)c(O)c1

    InChI

    1S/C24H40O3/c1-4-5-6-7-14-24(2,3)19-11-13-21(23(27)16-19)22-17-20(26)12-10-18(22)9-8-15-25/h11,13,16,18,20,22,25-27H,4-10,12,14-15,17H2,1-3H3/t18-,20-,22-/m1/s1

    InChI key

    YNZFFALZMRAPHQ-SYYKKAFVSA-N

    Gene Information

    human ... CNR1(1268) , CNR2(1269)
    rat ... Cnr1(25248)

    Application

    CP-55940 has been used as a cannabinoid agonists in Chinese hamster ovary (CHO) expressing cannabinoid receptor 2(CB2).

    Packaging

    10, 50 mg in glass bottle

    Biochem/physiol Actions

    CP-55940 is a nonclassical cannabinoids (NCCs), which lack the tetrahydropyran ring. CP-55940, a derivative of CP-47,497 is enantioselective. Due to its amphipathic nature, CP-55940 tethers in biological membrane making it favourable for the cannabinoid receptor interaction. CP-55940 belongs to the cyclohexylphenol category and modulates the brain lipidome leading to dysregulation especially during adolescence. It inhibits capsaicin-evoked sensitization of nociceptive and spinal dorsal horn neurons.
    CP-55940 is a selective cannabinoid receptor agonist.

    Features and Benefits

    This compound was developed by Pfizer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
    This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction.

    Pictograms

    GHS07

    Signal Word

    Warning

    Hazard Statements

    H336

    Target Organs

    Central nervous system

    Personal Protective Equipment

    dust mask type N95 (US),Eyeshields,Gloves

    RIDADR

    NONH for all modes of transport

    WGK Germany

    WGK 3

    Flash Point(F)

    Not applicable

    Flash Point(C)

    Not applicable