Description
Cordycepin, 10mg
Formal Name
3'-deoxy-adenosine
CAS Number
73-03-0
Synonyms
- 3'-Deoxyadenosine
- NSC 63984
- NSC 401022
Molecular Formula
C10H13N5O3
Formula Weight
251.2
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 2.5 mg/ml
- DMSO: 10 mg/ml
- DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml
λmax
210, 260 nm
SMILES
OC[C@@H]1C[C@@H](O)[C@H](N2C=NC3=C2N=CN=C3N)O1
InChi Code
InChI=1S/C10H13N5O3/c11-8-7-9(13-3-12-8)15(4-14-7)10-6(17)1-5(2-16)18-10/h3-6,10,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,10+/m0/s1
InChi Key
OFEZSBMBBKLLBJ-BAJZRUMYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 2 years
Cordycepin is a nucleoside analog found in C. sinensis that acts as a polyadenylation inhibitor when converted to cordycepin triphosphate, which inhibits ATP-dependent DNA and RNA synthesis. Cordycepin has a broad spectrum of biological activities, including anti-proliferative, pro-apoptotic, and anti-inflammatory effects. Cordycepin has been shown to reduce poly(A) tail length in mRNA at 10 μM and to activate AMPK kinase, leading to a reduction in mTOR signaling at 200 μM.
WARNING This product is not for human or veterinary use.