Collagenase II, 2 X 0.5 ML

SKU:
1148090-2X0.5ML
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    • Description

    Collagenase II, 2 X 0.5 ML

    United States Pharmacopeia (USP) Reference Standard

    Synonym(s):
    Clostridiopeptidase A, Collagenase from Clostridium histolyticum
    CAS Number:
    9001-12-1
    Enzyme Commission number:
    3.4.24.3 (BRENDA, IUBMB)
    MDL number:
    MFCD00130830
    NACRES:
    NA.24

    PROPERTIES

    grade

    pharmaceutical primary standard

    manufacturer/tradename

    USP

    format

    neat

    storage temp.

    −70°C

    General description

    This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.

    Biochem/physiol Actions

    Collagenase is activated by four gram atom calcium per mole enzyme. It is inhibited by ethylene glycol-bis(beta-aminoethyl ether) - N, N, N′,N′-tetraacetic acid, beta-mercaptoethanol, glutathione, thioglycolic acid and 8-hydroxyquinoline.

    Unit Definition

    One collagen digestion unit (CDU) liberates peptides from collagen from bovine achilles tendon equivalent in ninhydrin color to 1.0 μmole of leucine in 5 hours at pH 7.4 at 37 °C in the presence of calcium ions. One FALGPA hydrolysis unit hydrolyzes 1.0 μmole of furylacryloyl-Leu-Gly-Pro-Ala per min at 25°C. One Neutral Protease unit hydrolyzes casein to produce color equivalent to 1.0 μmole of tyrosine per 5 hr at pH 7.5 at 37°C. One Clostripain Unit hydrolyzes 1.0 μmole of BAEE per min at pH 7.6 at 25°C in the presence of DTT.

    Analysis Note

    These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

    SAFETY INFORMATION

    Signal Word

    Danger

    Hazard Statements

    H334

    Precautionary Statements

    P261 - P284 - P501

    Hazard Classifications

    Resp. Sens. 1

    Storage Class Code

    12 - Non Combustible Liquids

    WGK

    WGK 1

    Flash Point(F)

    Not applicable

    Flash Point(C)

    Not applicable