Chloramphenicol-Water Soluble, 100MG

SKU:
C3175-100MG
  • $102.00
  • Description

    Chloramphenicol-Water Soluble

    Synonym(s):
    Chloramphenicol, Chlornitromycin, Chlorocid, Chloromycetin, Cloramfenicol, D-(−)-threo-2-Dichloroacetamido-1-(4-nitrophenyl)-1,3-propanediol, D-(−)-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-β-(4-nitrophenyl)ethyl]acetamide, Chloromycetin, D-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-4-nitrophenethyl]aceta, Kloramfenikol
    NACRES:
    NA.76

    PROPERTIES

    product line

    BioReagent

    Quality Level

    200

    form

    powder

    technique(s)

    cell culture | mammalian: suitable

    solubility

    H2O: 50-500 mg/mL (stock solution)
    PBS: 50-500 mg/mL (stock solution)
    other salt solutions: not recommended

    antibiotic activity spectrum

    Gram-negative bacteria
    Gram-positive bacteria
    mycobacteria
    mycoplasma

    Mode of action

    protein synthesis | interferes

    Application

    Chloramphenicol-Water Soluble has been used:

    • as a supplement in Luria-Bertani (LB) medium to culture Escherichia coli[1]
    • as a supplement in LB agar to culture Citrobacter rodentium[2]
    • to culture Toxoplasma gondii[3]

    Packaging

    100 mg in glass bottle
    Package size based on chloramphenicol

    Biochem/physiol Actions

    Chloramphenicol is a natural product found in Streptomyces venezuelae.[4] It shows a broad range of antibiotic activity against Gram-negative and Gram-positive bacteria by binding to the peptidyl transferase loop of the ribosomal RNA to block the peptide bond formation.[5][6]

    Other Notes

    Formulated to contain approx. 100 mg chloramphenicol per gram of powder; balance 2-hydroxypropyl-β-cyclodextrin.
    Keep container tightly closed in a dry and well-ventilated place. Light sensitive. Keep in a dry place.

    SAFETY INFORMATION

    Signal Word

    Danger

    Hazard Statements

    H318 - H351 - H361fd

    Precautionary Statements

    P202 - P280 - P305 + P351 + P338 - P308 + P313 - P405 - P501

    Hazard Classifications

    Carc. 2 - Eye Dam. 1 - Repr. 2

    Storage Class Code

    11 - Combustible Solids

    WGK

    WGK 3

    Flash Point(F)

    Not applicable

    Flash Point(C)

    Not applicable

    Personal Protective Equipment

    dust mask type N95 (US), Eyeshields, Gloves