Abnormal CBD-d3 Internal standard, 100ug

SKU:
CAY-10009523-100ug
  • $39.00

    • Description

    Abnormal CBD-d3, CAY10429-d3 Item No. 10009523, 100 µg

     

    Technical Information
    Formal Name
    4-[(6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-1,3-benzenediol-5,5,5-d3
    Synonyms
    • Abn-CBD-d3
    • Abnormal Cannabidiol-d3
    Molecular Formula
    C21H27D3O2
    Formula Weight
    317.5
    Purity
    ≥99% deuterated forms (d1-d3)
    Formulation
    A solution in methyl acetate
    Solubility
    • DMF: 50 mg/ml
    • DMSO: 60 mg/ml
    • DMSO:PBS (pH 7.2)(1:3): 0.25 mg/ml
    • Ethanol: 35 mg/ml
    SMILES
    CC1=C[C@@H](C2=C(CCCCC([2H])([2H])[2H])C=C(O)C=C2O)[C@H](C(C)=C)CC1
    InChi Code
    InChI=1S/C21H30O2/c1-5-6-7-8-16-12-17(22)13-20(23)21(16)19-11-15(4)9-10-18(19)14(2)3/h11-13,18-19,22-23H,2,5-10H2,1,3-4H3/t18-,19+/m0/s1/i1D3
    InChi Key
    YWEZXUNAYVCODW-ORDZOMCNSA-N
    Shipping & Storage Information
    Storage
    -20°C
    Shipping
    Wet ice in continental US; may vary elsewhere
    Stability
    ≥ 1 year
     
    Product Description

    CAY10429-d3 contains three deuterium atoms at the terminal methyl position. It is intended for use as an internal standard for the quantification of CAY10429 by GC- or LC-mass spectrometry. Traditionally, the activity of cannabinoid (CB) agonists was thought to be transduced by a pair of G protein-coupled receptors, CB1 and CB2.1 CAY10429 (abnormal cannabidiol) is a synthetic regioisomer of cannabidiol that fails to elicit either CB1 or CB2 responsiveness and is without psychotropic activity. CAY10429 induces endothelium-dependent vasodilation via a CB1/CB2/nitric oxide-independent mechanism.2 At a dose of 20 µg/g in rats, CAY10429 showed hypotensive activity that could not be antagonized by cannabidiol or SR141716A. CAY10429 is therefore believed to activate a third type of CB receptor, provisionally called the non-CB1/CB2 endocannabinoid receptor. CAY10429 also acts via these receptors to regulate the migratory activity of murine BV-2 microglial cells, with an EC50 value of 600 nM.3

    WARNING This product is not for human or veterinary use.