Butylated Hydroxytoluene, Pharmaceutical Secondary Standard; Certified Reference Material

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PHR1117-1G
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    • Description

    Butylated Hydroxytoluene, Pharmaceutical Secondary Standard; Certified Reference Material

    Synonym(s):
    2,6-Di-tert-butyl-4-methylphenol, 2,6-Di-tert-butyl-p-cresol, BHT, Butylated hydroxytoluene, Butylhydroxytoluene, DBPC
    Linear Formula:
    [(CH3)3C]2C6H2(CH3)OH
    CAS Number:
    128-37-0
    Molecular Weight:
    220.35
    Beilstein:
    1911640
    EC Number:
    204-881-4
    MDL number:
    MFCD00011644
    PubChem Substance ID:
    329823138
    E Number:
    E321
    NACRES:
    NA.24

    grade

    certified reference material
    pharmaceutical secondary standard

    Quality Level

    300

    Agency

    traceable to Ph. Eur. B1215000
    traceable to USP 1092708

    vapor density

    7.6 (vs air)

    vapor pressure

    <0.01 mmHg ( 20 °C)

    CofA

    current certificate can be downloaded

    autoignition temp.

    878 °F

    technique(s)

    HPLC: suitable
    gas chromatography (GC): suitable

    bp

    265 °C (lit.)

    mp

    69-73 °C (lit.)

    application(s)

    cleaning products
    cosmetics
    food and beverages
    personal care
    pharmaceutical (small molecule)

    format

    neat

    storage temp.

    2-30°C

    SMILES string

    Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C

    InChI

    1S/C15H24O/c1-10-8-11(14(2,3)4)13(16)12(9-10)15(5,6)7/h8-9,16H,1-7H3

    InChI key

    NLZUEZXRPGMBCV-UHFFFAOYSA-N

    Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
    Butylated hydroxytoluene (BHT) is a phenolic antioxidant used as a food additive. It is frequently added to dried cereals, cooking oils and animal foods. BHT is also known to enhance the stability of pharmaceuticals, fat-soluble vitamins and cosmetics .

    Application

    These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

    Analysis Note

    These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

    Other Notes

    This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

    Footnote

    To see an example of a Certificate of Analysis for this material enter LRAB3695 in the slot below. This is an example certificate only and may not be the lot that you receive.

    SAFETY INFORMATION

    Pictograms

    GHS09

    Signal Word

    Warning

    Hazard Statements

    H410

    Precautionary Statements

    P273 - P391 - P501

    Hazard Classifications

    Aquatic Chronic 1

    Storage Class Code

    11 - Combustible Solids

    WGK

    WGK 2

    Flash Point(F)

    260.6 °F - open cup

    Flash Point(C)

    127 °C - open cup