Description
BSTFA (with 1% TMCS)
kit of 10 × 1 mL, analytical standard, Cerilliant®
Synonym(s):
N,O-Bis(trimethylsilyl)trifluoroacetamide, BSTFA
Linear Formula:
CF3C[=NSi(CH3)3]OSi(CH3)3
CAS Number:
25561-30-2
Molecular Weight:
257.40
Beilstein:
2050024
MDL number:
MFCD00008269
PubChem Substance ID:
329773102
NACRES:
NA.24
PROPERTIES
grade
analytical standard
Quality Level
100
reaction suitability
reagent type: derivatization reagent
reaction type: Acylations
packaging
kit of 10 × 1 mL
manufacturer/tradename
Cerilliant®
technique(s)
gas chromatography (GC): suitable
refractive index
n20/D 1.384 (lit.)
bp
45-50 °C/14 mmHg (lit.)
density
0.969 g/mL at 25 °C (lit.)
application(s)
forensics and toxicology
format
neat
storage temp.
−20°C
SMILES string
C[Si](C)(C)O\C(=N\[Si](C)(C)C)C(F)(F)F
InChI
1S/C8H18F3NOSi2/c1-14(2,3)12-7(8(9,10)11)13-15(4,5)6/h1-6H3/b12-7+
InChI key
XCOBLONWWXQEBS-KPKJPENVSA-N
Application
BSTFA (with 1% TMCS) may be used as a derivatizing agent in the following:
- Analysis of estrogenic compounds in water samples using gas chromatography coupled to mass spectrometry (GC-MS).[1]
- Quantification of α-pyrrolidinovalerophenone (α-PVP) and its metabolites in urine samples using gas chromatography coupled to mass spectrometry (GC-MS).[2]
Features and Benefits
- BSTFA is very versatile, reacting with a range of polar organic compounds and replacing active hydrogens with a −Si(CH3)3 (trimethylsilyl) group.
- Reacts rapidly and more completely than BSA.;
- TMCS increases the reactivity of BSTFA (or other silylation reagents).
- Amides and many secondary amines and hindered hydroxyls, incompletely derivatized by BSTFA alone, can be derivatized by adding 1-20% TMCS to BSTFA.
- Has good solvent properties and can function as a silylation reagent without additional solvents.
- Alternatively, the mixture is very soluble in most commonly used silylation solvents.
Legal Information
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
RELATED PRODUCTS
Related Product
Product No.
Description
Pricing
M-108
MTBSTFA (with 1% t-BDMCS), (with 1% t-BDMCS), ampule of 5 × 1 mL, analytical standard, Cerilliant®
M-132
MSTFA Reagent, ampule of 10 × 1.2 mL, analytical standard, Cerilliant®
SAFETY INFORMATION
Pictograms
GHS02,GHS07
Signal Word
Warning
Hazard Statements
H226 - H315 - H319
Precautionary Statements
P210 - P233 - P240 - P241 - P303 + P361 + P353 - P305 + P351 + P338
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2
Storage Class Code
3 - Flammable liquids
WGK
WGK 3
Flash Point(F)
75.2 °F - closed cup
Flash Point(C)
24.0 °C - closed cup
