Astec CHIROBIOTIC TAG, 25 cm x 4.6 mm I.D., 5 um particles, 1EA

SKU:
14024AST
On Sale
  • Now: $3,029.11
    Was: $3,170.00
    — You save $140.89

    • Description

    Astec® CHIROBIOTIC® TAG Chiral (5 μm) HPLC Columns

    L × I.D. 25 cm × 4.6 mm, HPLC Column

    About This Item

    UNSPSC Code:
    41115700
    eCl@ss:
    32110501
    NACRES:
    SB.52

    Properties

    product name

    Astec® CHIROBIOTIC® TAG Chiral HPLC Column, 5 μm particle size, L × I.D. 25 cm × 4.6 mm

    material

    stainless steel column

    Quality Level

    100

    agency

    suitable for USP L63

    description

    HPLC column

    product line

    Astec®

    packaging

    pkg of 1 ea

    manufacturer/tradename

    Astec®

    parameter

    0-45 °C temperature
    241 bar pressure (3500 psi)

    technique(s)

    HPLC: suitable
    LC/MS: suitable

    L × I.D.

    25 cm × 4.6 mm

    matrix

    High-purity silica gel particle platform
    fully porous particle

    matrix active group

    teicoplanin aglycone phase

    particle size

    5 μm

    pore size

    100 Å

    operating pH range

    3.0-6.8

    separation technique

    chiral

    Description

    General description

    The removal of three carbohydrate moieties gives CHIROBIOTIC® TAG complementary selectivity to CHIROBIOTIC® T. Resolution is enhanced toward many of the amino acids, α, β, γ and cyclic, and especially sulfur-containing methionine, histidine and cysteine. A number of neutral molecules like the oxazolidinones, hydantoins and diazepines have shown enhanced resolution and, more remarkably, in the single solvents like methanol, ethanol and acetonitrile. Some acidic molecules have also shown increased selectivity.

    • Bonded phase: Teicoplanin aglycone
    • Operating pH range: 3.0 - 6.8
    • Particle diameter: 5, 10 or 16 μm
    • Pore size: 100 Å

    Application


      • High-performance liquid chromatographic enantioseparation of 2-aminomono- and dihydroxycyclopentanecarboxylic and 2-aminodihydroxycyclohexanecarboxylic acids on macrocyclic glycopeptide-based phases.: This study emphasizes the effectiveness of the Astec® CHIROBIOTIC® TAG Chiral HPLC Column in the enantioseparation of complex cyclic amino acids. The methodology detailed provides profound insights into the chirality aspects of biochemical molecules, which is crucial for the synthesis of novel pharmaceutical agents and the study of biochemical pathways. This research supports analytical chemists in academia focused on developing chiral analytical methods and advancing chemical synthesis (Berkecz et al., 2009).


    Recommended products

    Discover LiChropur reagents ideal for HPLC or LC-MS analysis

    Legal Information

    Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
    CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC

    Safety Information

    wgk_germany

    WGK 3

    flash_point_f

    Not applicable

    flash_point_c

    Not applicable