Ascorbic Acid Pharmaceutical Secondary Standard; Certified Reference Material

SKU:
PHR1008-2G
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    • Description

    Ascorbic Acid Pharmaceutical Secondary Standard; Certified Reference Material

    Synonym(s):
    L-Ascorbic acid, Antiscorbutic factor, Vitamin C, L-Threoascorbic acid
    Empirical Formula (Hill Notation):
    C6H8O6
    CAS Number:
    50-81-7
    Molecular Weight:
    176.12
    Beilstein/REAXYS Number:
    84272
    EC Number:
    200-066-2
    MDL number:
    MFCD00064328
    PubChem Substance ID:
    329823039
    E Number:
    E300
    NACRES:
    NA.24

    Quality Level

    300

    grade

    certified reference material
    pharmaceutical secondary standard

    CofA

    current certificate can be downloaded

    application(s)

    HPLC: suitable
    gas chromatography (GC): suitable

    mp

    190-194 °C (dec.)

    Featured Industry

    Cleaning Products
    Cosmetics
    Food and Beverages
    Personal Care
    Pharmaceutical (small molecule)
    Vitamins, Nutraceuticals, and Natural Products

    pharmacopeia traceability

    traceable to BP 461
    traceable to PhEur A1300000
    traceable to USP 1043003

    SMILES string

    OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

    InChI

    1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

    InChI key

    CIWBSHSKHKDKBQ-JLAZNSOCSA-N

    General description

    Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Ascorbic acid is a powerful antioxidant and is widely used in pharmaceutical formulations. It has proven to have a beneficial effect on age-related diseases such as cancer, atherosclerosis, ocular, neurodegenerative diseases, etc. It is mainly involved in the formation and maintenance of collagen. The prolonged deficiency of ascorbic acid in diet may result in scurvy.

    Application

    Ascorbic Acid may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using hydrophilic interaction chromatography.

    Biochem/physiol Actions

    Ascorbic Acid, also known as Vitamin C, is a six-carbon lactone produced by plants and some animal species but not by humans and other primates. Ascorbic acid functions as an enzymatic cofactor for multiple enzymes, serving as an electron donor for monooxygenases and dioxygenases. Ascorbic acid also functions as a powerful antioxidant, particularly in regards to reactive oxygen species.

    Analysis Note

    These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

    Other Notes

    This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

    Footnote

    To see an example of a Certificate of Analysis for this material enter LRAC2886 in the slot below. This is an example certificate only and may not be the lot that you receive.

    RIDADR

    NONH for all modes of transport

    WGK Germany

    WGK 1

    Flash Point(F)

    Not applicable

    Flash Point(C)

    Not applicable