Ascentis Express 90 A F5 (2.7 um) HPLC Columns, L x I.D. 15 cm x 4.6 mm, HPLC Column

SKU:
53591-U
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    • Description

    Ascentis® Express 90 Å F5 (2.7 μm) HPLC Columns

    L × I.D. 15 cm × 4.6 mm, HPLC Column

    Synonym(s):

    Core-shell (SPP) Fused Core PFP HPLC column

    About This Item

    UNSPSC Code:
    41115700
    eCl@ss:
    32110501
    NACRES:
    SB.52

    Properties

    product name

    Ascentis® Express F5, 2.7 μm HPLC Column, 2.7 μm particle size, L × I.D. 15 cm × 4.6 mm

    material

    stainless steel column

    Quality Level

    100

    agency

    suitable for USP L43

    product line

    Ascentis®

    feature

    endcapped

    manufacturer/tradename

    Ascentis®

    packaging

    1 ea of

    parameter

    60 °C temp. range
    600 bar max. pressure (9000 psi)

    technique(s)

    HPLC: suitable
    LC/MS: suitable
    UHPLC-MS: suitable
    UHPLC: suitable

    L × I.D.

    15 cm × 4.6 mm

    surface area

    135 m2/g

    impurities

    <5 ppm metals

    matrix

    Fused-Core particle platform
    superficially porous particle

    matrix active group

    PFP (pentafluorophenyl) phase

    particle size

    2.7 μm

    pore size

    90 Å pore size

    operating pH

    2-8

    application(s)

    food and beverages

    separation technique

    reversed phase

    Description

    General description

    The pentafluorophenylpropyl stationary phase of Ascentis Express F5 provides a stable reversed phase packing with electron-deficient phenyl rings due to the presence of electronegative fluorines.In addition to forming pi-pi and mildly steric interactions, F5 phases also retain compounds by polar interactions. Ascentis Express F5 can be used for basic, acidic, or neutral compounds with alternate selectivity from C18.

    Application


      • Liquid chromatographic determination of lumacaftor in the presence of ivacaftor and identification of five novel degradation products using high-performance liquid chromatography ion trap time-of-flight mass spectrometry.: This study demonstrates the use of high-performance liquid chromatography (HPLC) with ion trap time-of-flight mass spectrometry for the determination of lumacaftor in the presence of ivacaftor. The research identifies five novel degradation products, showcasing the advanced analytical capabilities of the Ascentis® Express F5, 2.7 µm HPLC Column for complex mixtures and degradation studies (Özcan et al., 2023).

      • Stability-indicating LC-MS/MS and LC-DAD methods for robust determination of tasimelteon and high resolution mass spectrometric identification of a novel degradation product.: This paper details the development of stability-indicating methods using LC-MS/MS and LC-DAD for the determination of tasimelteon. It highlights the robustness and sensitivity of these methods in identifying novel degradation products, with the Ascentis® Express F5 column playing a crucial role in separation efficiency and stability analysis (Özcan et al., 2020).

      • Recent trends in ultra-fast HPLC: new generation superficially porous silica columns.: This review article discusses recent advancements in ultra-fast HPLC, focusing on new generation superficially porous silica columns, including the Ascentis® Express F5, 2.7 µm HPLC Column. It provides insights into the enhanced performance, speed, and efficiency of these columns in high-throughput analytical applications (Ali et al., 2012).

    Legal Information

    Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany

    Safety Information

    wgk_germany

    WGK 3

    flash_point_f

    Not applicable

    flash_point_c

    Not applicable