Andrographolide, analytical standard, 5mg

SKU:
90281-5MG
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    • Description

    Andrographolide, analytical standard, 5mg

    Synonym(s):
    ent-(3β,12E,14R)-3,14,19-Trihydroxy-8(17),12-labdadien-16,15-olide, Andrographis, (3E,4S)-3-[2-[(1R,4aS,5R,6R,8aS)-Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-2(3H)-furanone
    Empirical Formula (Hill Notation):
    C20H30O5
    CAS Number:
    5508-58-7
    Molecular Weight:
    350.45
    EC Number:
    226-852-5
    MDL number:
    MFCD07778082
    PubChem Substance ID:
    329769897
    NACRES:
    NA.24

    grade

    analytical standard

    Quality Level

    100

    assay

    ≥95% (HPLC)

    form

    neat

    shelf life

    limited shelf life, expiry date on the label

    application(s)

    HPLC: suitable
    gas chromatography (GC): suitable

    Featured Industry

    Food and Beverages

    format

    neat

    SMILES string

    C[C@@]1(CO)[C@H](O)CC[C@@]2(C)[C@H](C\C=C3/[C@H](O)COC3=O)C(=C)CC[C@H]12

    InChI

    1S/C20H30O5/c1-12-4-7-16-19(2,9-8-17(23)20(16,3)11-21)14(12)6-5-13-15(22)10-25-18(13)24/h5,14-17,21-23H,1,4,6-11H2,2-3H3/b13-5+/t14-,15-,16+,17-,19+,20+/m1/s1

    Inchi Key

    BOJKULTULYSRAS-OTESTREVSA-N

    Andrographolide is a major bioactive component of Andrographis paniculata Nees. which is a popular Chinese and Indian medicine. It belongs to the terpenoid class of compounds.

    Application

    Andrographolide may be used as a reference standard for the determination of andrographolide in:
    • Leaves of Andrographis paniculata by soxhlet extraction-recrystallization-column chromatography purification followed by analyses using reversed phase high performance liquid chromatography (RP-HPLC) as well as gas chromatography-mass spectrometry (GC-MS).
    • Roots of Andrographis paniculata by HPLC with diode array detection (DAD), gas chromatography-mass spectrometry (GC-MS) and LC coupled to tandem mass spectrometry (MS/MS) equipped with electrospray ionization (ESI) and multiple reaction monitoring (MRM) mode of detection.
    • Stems of Andrographis paniculata by ultra-HPLC combined coupled to triple quadrupole-linear ion trap mass spectrometry (QqQLIT-ESI-MS/MS) with MRM detection.
    • Rat plasma samples by protein precipitation and subsequent ESI-LC-MS/MS determination using MRM detection.
    Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

    Packaging

    Bottomless glass bottle. Contents are inside inserted fused cone.

    RIDADR

    NONH for all modes of transport

    WGK Germany

    WGK 3

    Flash Point(F)

    Not applicable

    Flash Point(C)

    Not applicable