Andrographolide, 500mg

SKU:
365645-500MG
  • $203.00

    • Description

    Andrographolide, 98%, 500mg

    Empirical Formula (Hill Notation):
    C20H30O5
    CAS Number:
    5508-58-7
    Molecular Weight:
    350.45
    Beilstein/REAXYS Number:
    42762
    EC Number:
    226-852-5
    MDL number:
    MFCD07778082
    PubChem Substance ID:
    24862550
    NACRES:
    NA.22

    Quality Level

    100

    assay

    98%

    optical activity

    [α]20/D −126°, c = 1.5 in acetic acid

    mp

    229-232 °C (lit.)

    SMILES string

    C[C@@]1(CO)[C@H](O)CC[C@@]2(C)[C@H](C\C=C3/[C@H](O)COC3=O)C(=C)CC[C@H]12

    InChI

    1S/C20H30O5/c1-12-4-7-16-19(2,9-8-17(23)20(16,3)11-21)14(12)6-5-13-15(22)10-25-18(13)24/h5,14-17,21-23H,1,4,6-11H2,2-3H3/b13-5+/t14-,15-,16+,17-,19+,20+/m1/s1

    InChI key

    BOJKULTULYSRAS-OTESTREVSA-N

    Andrographolide, a bioactive diterpene lactone, is the main constituent of Andrographis paniculata, a plant used in traditional medicines. It is known to have different biological activities such as anti-inflammatory, anti-malarial, anti-cancer and hepatoprotective activity. It also shows potent anti-viral effect against dengue virus.

    Packaging

    100 mg in clear glass bottle
    500 mg in amber glass bottle

    Biochem/physiol Actions

    Diterpenoid lactone with anti-inflammatory properties. It blocks T-cell proliferation to allogenic stimuli and the chemotactic migration of macrophages induced by complement. Blocks the proliferation of several cancer cell lines in vitro.

    Personal Protective Equipment

    dust mask type N95 (US),Eyeshields,Gloves

    RIDADR

    NONH for all modes of transport

    WGK Germany

    WGK 3

    Flash Point(F)

    Not applicable

    Flash Point(C)

    Not applicable