AM251 (HPLC), solid, 10MG

SKU:
A6226-10MG
  • $279.00

    • Description

    AM251>98% (HPLC), solid, 10MG

    Synonym(s):
    1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide
    Empirical Formula (Hill Notation):
    C22H21N4OCl2I
    CAS Number:
    183232-66-8
    Molecular Weight:
    555.24
    MDL number:
    MFCD01861181
    PubChem Substance ID:
    24891069

    Quality Level

    100

    assay

    >98% (HPLC)

    form

    solid

    color

    white

    solubility

    DMSO: >10 mg/mL
    H2O: insoluble

    originator

    Sanofi Aventis

    SMILES string

    Cc1c(nn(-c2ccc(Cl)cc2Cl)c1-c3ccc(I)cc3)C(=O)NN4CCCCC4

    InChI

    1S/C22H21Cl2IN4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-7-16(23)13-18(19)24)21(14)15-5-8-17(25)9-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)

    InChI key

    BUZAJRPLUGXRAB-UHFFFAOYSA-N

    Gene Information

    mouse ... Cnr1(12801) , Cnr2(12802)
    rat ... Cnr1(25248)

    AM251, a CB1 cannabinoid receptor antagonist, has been used in a study to determine its interaction with hippocampal neurons to enhance spatial memory in mice.

    Packaging

    10, 50 mg in glass bottle

    Biochem/physiol Actions

    AM251 is a CB1 cannabinoid receptor antagonist.

    Features and Benefits

    This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
    This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

    Other Notes

    Salt content may vary.

    Personal Protective Equipment

    dust mask type N95 (US),Eyeshields,Gloves

    RIDADR

    NONH for all modes of transport

    WGK Germany

    WGK 3

    Flash Point(F)

    Not applicable

    Flash Point(C)

    Not applicable