MilliporeSigma
Alpha Lipoic Acid, United States Pharmacopeia (USP) Reference Standard, 500MG
- SKU:
- 1368201-500MG
Description
Alpha Lipoic Acid, United States Pharmacopeia (USP) Reference Standard, 500MG
United States Pharmacopeia (USP) Reference Standard
Synonym(s):
6,8-Dithiooctanoic acid, (±)-α-Lipoic acid, (±)-1,2-Dithiolane-3-pentanoic acid, DL-6,8-Thioctic acid, DL-α-Lipoic acid, Lip(S2)
Empirical Formula (Hill Notation):
C8H14O2S2
CAS Number:
1077-28-7
Molecular Weight:
206.33
Beilstein:
81853
MDL number:
MFCD00005474
PubChem Substance ID:
329750249
NACRES:
NA.24
PROPERTIES
grade
pharmaceutical primary standard
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
SMILES string
OC(=O)CCCCC1CCSS1
InChI
1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)
InChI key
AGBQKNBQESQNJD-UHFFFAOYSA-N
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
Biochem/physiol Actions
Antioxidant and coenzyme needed for the activity of enzyme complexes such as those of pyruvate dehydrogenase and glycine decarboxylase. Exogenous thioctic acid is reduced intracellularly by two or more enzymes. The reduced form then influences a number of cell processes by direct radical scavenging, recycling of other antioxidants, increasing glutathione synthesis, and modulating transcription factor activity particularly that of NF-κB. Decreases the phagocytosis of myelin by macrophages.
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
SAFETY INFORMATION
Signal Word
Warning
Hazard Statements
H302 - H315 - H317 - H319 - H411
Precautionary Statements
P273 - P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable