Aflatoxin B1-13 C17, 1.2mL

SKU:
CAY-31260
  • $1,184.00

    • Description

    Aflatoxin B1-13 C17, 1.2mL

    LETTER OF ASSURANCE FOR DOMESTIC SHIPMENTS OF ITEMS must be completed before purchase. 

    LETTER OF ASSURANCE

    Aflatoxin B1-13C17 (AFB1-13C17) is intended for use as an internal standard for the quantification of AFB1 (Item No. 11293) by GC- or LC-MS. AFB1 is a genotoxic mycotoxin that has been found in Aspergillus.1,2 It induces the formation of DNA adducts in rat liver microsomes.1 AFB1 induces transversion of guanine to thymine at codon 29 of the p53 tumor suppressor gene, a mutation commonly seen in hepatocellular carcinoma patients living in regions with high levels of aflatoxin contamination, in HepG2 cells.2 In vivo, AFB1 (50 and 100 µg/kg) induces hepatocellular carcinoma tumor formation in rats.3

    WARNING This product is not for human or veterinary use.

    Formal Name
    (6aR,9aS)-4-(methoxy-13C)-2,3,6a,9a-tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11-dione-1,2,3,3a,3b,4,5,5a,6a,8,9,9a,9b,9c,11,11a-13C16
    CAS Number
    1217449-45-0
    Synonyms
    • AFB1-13C17
    Molecular Formula
    [13C]17H12O6
    Formula Weight
    329.1
    Purity
    ≥98%
    Formulation(Request formulation change)
    A solution in acetonitrile
    • Acetonitrile: soluble
    SMILES
    O=[13C]1[13C]2=[13C]([13CH2][13CH2][13C]2=O)[13C]3=[13C]([13C]([13C@@]([13CH]=[13CH]O4)([H])[13C@@]4([H])O5)=[13C]5[13CH]=[13C]3O[13CH3])O1
    InChi Code
    InChI=1S/C17H12O6/c1-20-10-6-11-14(8-4-5-21-17(8)22-11)15-13(10)7-2-3-9(18)12(7)16(19)23-15/h4-6,8,17H,2-3H2,1H3/t8-,17+/m0/s1/i1+1,2+1,3+1,4+1,5+1,6+1,7+1,8+1,9+1,10+1,11+1,12+1,13+1,14+1,15+1,16+1,17+1
    InChi Key
    OQIQSTLJSLGHID-DENWKYDXSA-N
    Shipping & Storage Information
    Storage
    -20°C
    Shipping
    Room Temperature in continental US; may vary elsewhere
    Stability
    ≥ 1 year