Description
a-Tocopherol synthetic, (HPLC), 5 grams, synthetic, ≥96% (HPLC)
Synonym(s):
DL-all-rac-α-Tocopherol, Vitamin E
Empirical Formula (Hill Notation):
C29H50O2
CAS Number:
10191-41-0
Molecular Weight:
430.71
Beilstein:
94012
EC Number:
233-466-0
MDL number:
MFCD00006848
eCl@ss:
34058016
PubChem Substance ID:
24900118
NACRES:
NA.77
PROPERTIES
biological source
synthetic
Quality Level
200
Assay
≥96% (HPLC)
form
liquid
technique(s)
HPLC: suitable
color
faint brown to brown
yellow to very dark yellow
solubility
H2O: insoluble
acetone: miscible
chloroform: miscible
ethanol: miscible
vegetable oils: miscible
density
0.950 g/mL at 20 °C (lit.)
storage temp.
2-8°C
SMILES string
CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(O)c(C)c(C)c2O1
InChI
1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3
InChI key
GVJHHUAWPYXKBD-UHFFFAOYSA-N
DESCRIPTION
Application
(±)-α-Tocopherol has been used for preparing mycobacterial emulsions. It has also been used to study its immunomodulatory effect on influenza virus.
Biochem/physiol Actions
Tocopherols (vitamin E) comprise of a series (α, β, γ and δ) of chiral compounds that differ by the methylation degree of the phenol moiety of the chromanol ring. They function as lipid soluble antioxidants and protect cell membranes from oxidative damage. α-tocopherols are favorably absorbed by humans and their nicotinate salts can function as vitamin E supplements. Studies have also reported that vitamin E can prevent cell damage caused by pharmacologically induced epilepsy in rats.
Preparation Note
(±)-α-Tocopherol is miscible with chloroform, ethanol, ether, acetone, and vegetable oils. However, it is practically insoluble in water. (±)-α-Tocopherol is unstable under alkaline conditions.
SAFETY INFORMATION
Signal Word
Warning
Hazard Statements
H317
Precautionary Statements
P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
Hazard Classifications
Skin Sens. 1
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves