a-Tocopherol synthetic, (HPLC), 5 grams

SKU:
T3251-5G
  • $16.70

    • Description

    a-Tocopherol synthetic, (HPLC), 5 grams, synthetic, ≥96% (HPLC)

    Synonym(s):
    DL-all-rac-α-Tocopherol, Vitamin E
    Empirical Formula (Hill Notation):
    C29H50O2
    CAS Number:
    10191-41-0
    Molecular Weight:
    430.71
    Beilstein:
    94012
    EC Number:
    233-466-0
    MDL number:
    MFCD00006848
    eCl@ss:
    34058016
    PubChem Substance ID:
    24900118
    NACRES:
    NA.77

    PROPERTIES

    biological source

    synthetic

    Quality Level

    200

    Assay

    ≥96% (HPLC)

    form

    liquid

    technique(s)

    HPLC: suitable

    color

    faint brown to brown
    yellow to very dark yellow

    solubility

    H2O: insoluble
    acetone: miscible
    chloroform: miscible
    ethanol: miscible
    vegetable oils: miscible

    density

    0.950 g/mL at 20 °C (lit.)

    storage temp.

    2-8°C

    SMILES string

    CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(O)c(C)c(C)c2O1

    InChI

    1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3

    InChI key

    GVJHHUAWPYXKBD-UHFFFAOYSA-N

    DESCRIPTION

    Application

    (±)-α-Tocopherol has been used for preparing mycobacterial emulsions. It has also been used to study its immunomodulatory effect on influenza virus.

    Biochem/physiol Actions

    Tocopherols (vitamin E) comprise of a series (α, β, γ and δ) of chiral compounds that differ by the methylation degree of the phenol moiety of the chromanol ring. They function as lipid soluble antioxidants and protect cell membranes from oxidative damage. α-tocopherols are favorably absorbed by humans and their nicotinate salts can function as vitamin E supplements. Studies have also reported that vitamin E can prevent cell damage caused by pharmacologically induced epilepsy in rats.

    Preparation Note

    (±)-α-Tocopherol is miscible with chloroform, ethanol, ether, acetone, and vegetable oils. However, it is practically insoluble in water. (±)-α-Tocopherol is unstable under alkaline conditions.

    SAFETY INFORMATION

    Signal Word

    Warning

    Hazard Statements

    H317

    Precautionary Statements

    P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364

    Hazard Classifications

    Skin Sens. 1

    Storage Class Code

    10 - Combustible liquids

    WGK

    WGK 1

    Personal Protective Equipment

    dust mask type N95 (US), Eyeshields, Gloves