a-Hydroxymidazolam-d4 solution 100 ug/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant

SKU:
H-921-1ML
  • $346.00

    • Description

    α-Hydroxymidazolam-d4 solution

    100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

    Empirical Formula (Hill Notation):
    C18D4H9ClFN3O
    Molecular Weight:
    345.79
    EC Number:
    200-659-6
    MDL number:
    MFCD08276448
    PubChem Substance ID:
    329815261
    NACRES:
    NA.24

    PROPERTIES

    grade

    certified reference material

    Quality Level

    300

    form

    liquid

    feature

    Snap-N-Spike®/Snap-N-Shoot®

    packaging

    ampule of 1 mL

    manufacturer/tradename

    Cerilliant®

    concentration

    100 μg/mL in methanol

    technique(s)

    gas chromatography (GC): suitable
    liquid chromatography (LC): suitable

    application(s)

    clinical testing

    format

    single component solution

    storage temp.

    2-8°C

    SMILES string

    [2H]c1c([2H])c([2H])c(c(F)c1[2H])C2=NCc3cnc(CO)n3-c4ccc(Cl)cc24

    InChI

    1S/C18H13ClFN3O/c19-11-5-6-16-14(7-11)18(13-3-1-2-4-15(13)20)22-9-12-8-21-17(10-24)23(12)16/h1-8,24H,9-10H2/i1D,2D,3D,4D

    InChI key

    QHSMEGADRFZVNE-RHQRLBAQSA-N

    General description

    This internal standard is suitable for midazolam testing or isotope dilution methods by GC/MS or LC/MS for clinical toxicology, urine drug testing, pain prescription monitoring, or forensic analysis applications.

    It is an internal standard of α-hydroxymidazolam, a major metabolite of the benzodiazepine midazolam, formed upon its metabolism by cytochrome P450 3A (CYP3A) isoenzymes.

    Application

    The Certified Spiking Solution® is suitable for quantitative testing of α-Hydroxymidazolam by HPLC, GC/MS, or LC-MS/MS methods in forensic analysis, clinical toxicology, urine drug testing, and Cannabis potency or impurity profiling testing applications.

    The Certified Reference Material (CRM) in solution can also be used as follows:

    • Liquid chromatography-tandem mass spectrometry (LC–MS/MS) method based determination of 12 psychotropic drugs and their metabolites in guinea pig hair samples
    • Multiresidue analysis of 18 benzodiazepines in human blood and hair samples using LC–MS/MS
    • Detection and estimation of 21 benzodiazepines and three z-drugs from human hair samples after their two-step extraction by LC–MS/MS
    • Simultaneous analysis of 54 benzodiazepine and three z-drug residues from human urine and blood samples by ultra high-performance liquid chromatography- triple quadrupole tandem mass spectrometry (UHPLC-QqQ-MS/MS) method
    • Analysis of 26 compounds, comprising 18 benzodiazepines, seven benzodiazepine metabolites, and one z-drug from dried blood spot (DBS) cards using LC-MS/MS

    Features and Benefits

    • Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
    • Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
    • Rigorously tested through real-time stability studies to ensure accuracy and shelf life
    • Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
    • Flame sealed under argon into ampoules for long-term shelf life
    • Offered in a convenient, DEA-exempt format to improve laboratory efficiency

    Legal Information

    CERILLIANT is a registered trademark of Cerilliant Corporation
    CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
    Snap-N-Shoot is a registered trademark of Cerilliant Corporation
    Snap-N-Spike is a registered trademark of Cerilliant Corporation

    SAFETY INFORMATION

    Pictograms

    GHS02,GHS06,GHS08

    Signal Word

    Danger

    Hazard Statements

    H225 - H301 + H311 + H331 - H370

    Precautionary Statements

    P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311

    Hazard Classifications

    Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

    Target Organs

    Eyes

    Storage Class Code

    3 - Flammable liquids

    WGK

    WGK 1

    Flash Point(F)

    49.5 °F - closed cup

    Flash Point(C)

    9.7 °C - closed cup