MilliporeSigma
7-(Diethylamino)coumarin-3-carbohydrazide BioReagent, suitable for fluorescence, 25MG
- SKU:
- 36798-25MG-F
Description
7-(Diethylamino)coumarin-3-carbohydrazide
BioReagent, suitable for fluorescence, ≥95% (HPCE)
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CAS Number 100343-98-4
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Empirical Formula (Hill Notation) C14H17N3O3
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Molecular Weight 275.30
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Beilstein/REAXYS Number 5574454
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MDL number MFCD00467583
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PubChem Substance ID 57649662
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NACRES NA.32
Properties
Related Categories | Alphabetical, Analytical Reagents, Analytical/Chromatography, Biochemicals and Reagents, Carbohydrate Labels,
Carbohydrate Labels for Chromatography, Derivatization Reagents, Derivatization Reagents HPLC, Detection, Fluorescence, Fluorescent Labels, Fluorescent Probes, Labels, Particles and Stains, Functional Group Reactive Labels, Functional Group Reactive Labels for Chromatography, Hydrazides, Luminescent Compounds/Detection, Wavelength Index
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Quality Level | 100 |
product line | BioReagent |
assay | ≥95% (HPCE) |
solubility | DMF: soluble |
- | acetonitrile: soluble |
- | chloroform: soluble |
- | methanol: soluble |
fluorescence | λex 450 nm; λem 468 nm in methanol |
suitability | suitable for fluorescence |
SMILES string | CCN(CC)c1ccc2C=C(C(=O)NN)C(=O)Oc2c1 |
InChI | 1S/C14H17N3O3/c1-3-17(4-2)10-6-5-9-7-11(13(18)16-15)14(19)20-12(9)8-10/h5-8H,3-4,15H2,1-2H3,(H,16,18) |
InChI key | LYBMHAINSFEHRL-UHFFFAOYSA-N |
Safety Information
General description
7-(Diethylamino)coumarin-3-carbohydrazide is a coumarin-hydrazide reagent typically used as a fluorescent chemical probe for labeling of cellular carbonyls.[2]
Application
7-(Diethylamino)coumarin-3-carbohydrazide is used for derivatization and detection of carboxylic acid and carbonylated molecules such as lipid peroxidation products (LPP) by electrospray ionization-mass spectrometry (ESI-MS) in positive ion mode.[3] It may be used as a fluorescent label for the determination of lipid aldehydes in food products by normal phase liquid chromatography (NPLC) coupled to ESI-MS and fluorescent detector (FLD)[4] and for the derivatization of monoterpene alcohols in urine prior to analysis by high performance liquid chromatography(HPLC) with FLD coupled to ESI-MS.[6]
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.