25-hydroxy Vitamin D2

SKU:
CAY-12078-1MG
  • $131.00

    • Description

    25-hydroxy Vitamin D2

    Product Description

    25-hydroxy Vitamin D2 is a metabolite of vitamin D2 (Item No. 11791).1 It is formed from vitamin D2 by the cytochrome P450 (CYP) isoforms CYP2R1 and CYP27A1, which have 25-hydroxylase activity, and is bound to vitamin D binding protein (DBP) and albumin in the liver, then secreted into the bloodstream.2 25-hydroxy Vitamin D2 is transported to the kidney, where it is preferentially 24-hydroxylated by CYP24A1 to produce 24,25-dihydroxy vitamin D2.2 It can also be hydroxylated by CYP27B1 to produce 1,25-dihydroxy vitamin D2.2,1 Serum levels of 25-hydroxy vitamin D2 have been used as a marker of vitamin D status.3

    WARNING This product is not for human or veterinary use.

    Technical Information
    Formal Name
    4-methylene-3-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,2E,4S)-5-hydroxy-1,4,5-trimethyl-2-hexenyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-cyclohexanol
    CAS Number
    21343-40-8
    Synonyms
    • Ercalcidiol
    • 25-Hydroxyergocalciferol
    • 25(OH)-Vitamin D2
    Molecular Formula
    C28H44O2
    Formula Weight
    412.7
    Purity
    ≥98%
    Formulation(Request formulation change)
    A crystalline solid
    Solubility(Learn about Variance in Solubility)
    • DMF: 20 mg/ml
    • DMSO: 20 mg/ml
    • Ethanol: 20 mg/ml
    • Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml
    λmax
    211, 264 nm
    SMILES
    C=C1CC[C@H](O)C/C1=C\C=C2CCC[C@@]3(C)[C@@]\2([H])CC[C@]3([H])[C@H](C)/C=C/[C@H](C)C(C)(O)C
    InChi Code
    InChI=1S/C28H44O2/c1-19-10-14-24(29)18-23(19)13-12-22-8-7-17-28(6)25(15-16-26(22)28)20(2)9-11-21(3)27(4,5)30/h9,11-13,20-21,24-26,29-30H,1,7-8,10,14-18H2,2-6H3/b11-9+,22-12-,23-13+/t20-,21+,24+,25-,26+,28-/m1/s1
    InChi Key
    KJKIIUAXZGLUND-UURWAHJLSA-N
    Shipping & Storage Information
    Storage
    -20°C
    Shipping
    Wet ice in continental US; may vary elsewhere
    Stability
    ≥ 4 years