PLEASE NOTE: We will be closed Monday 11.11.2024 in observance of Veterans' Day.

2-Methyltetrahydrofuran (100mL)

SKU:
673277-100ML
  • $129.00

    • Description

    673277 Sigma-Aldrich

    2-Methyltetrahydrofuran

    BioRenewable, anhydrous, ≥99%, Inhibitor-free

    Synonym: 2-MeTHF, Tetrahydro-2-methylfuran, Tetrahydrosilvan

    • CAS Number 96-47-9

       

    • Empirical Formula (Hill Notation) C5H10O

       

    • Molecular Weight 86.13

       

    •  Beilstein Registry Number 102448

       

    •  EC Number 202-507-4

       

    •  MDL number MFCD00005367

    Description

    Features and Benefits

    Greener alternative for THF, DCM, DMSO, and MTBE

    Packaging

    1, 2 L in Sure/Seal™

    100, 12×100 mL in Sure/Seal™

    200 L in Pure-Pac™ 2

    Application

    2-Methyltetrahydrofuran may be used as solvent for phosphatidylserine synthesis.[1]
    It may be used as an alternative solvent to:
    • Dimethyl sulfoxide (DMSO) or methyl tert-butyl ether (MTBE) in the C-C bond forming reactions catalyzed by lyase enzyme.[6]
    • Tetrahydrofuran (THF) in the reaction between Grignard reagents and carbonyl compounds.[7]
    • Methylene chloride in some biphasic reactions.[8]

    Green Alternatives to DCM and THF from Renewable resources

    2-Methyltetrahydrofuran (2-MeTHF): A Biomass-Derived Solvent with Broad Application in Organic Chemistry

    General description

    2-Methyltetrahydrofuran (2-MTHF), a 2-methyl substituted tetrahydrofuran, is a biomass derived solvent. It is a potential greener solvent alternative for organic synthesis.[2] It shows resistance to reduction by lithium making it a promising candidate as electrolytes in lithium batteries.[3] Its polarity and Lewis base strength is intermediate between tetrahydrofuran (THF) and diethyl ether.[4] The ring opening reaction of 2-MTHF has been studied using acid chloride and iodide.[5]

    Properties

    Related Categories Anhydrous Solvents, Building Blocks, C4 to C7, Chemical Synthesis, Furans,
    More...
    grade anhydrous
    InChI Key JWUJQDFVADABEY-UHFFFAOYSA-N
    assay ≥99%
    expl. lim. 0.34-6.3 % ((lit.))
    greener alternative product characteristics Safer Solvents and Auxiliaries
    Learn more about the Principles of Green Chemistry.
    impurities ≤0.002% water
     - ≤0.005% water (100 mL pkg)
    evapn. residue ≤0.0003%
    refractive index n20/D 1.406(lit.)
    bp 78-80 °C(lit.)
    mp -136 °C (lit.)
    density 0.86 g/mL at 25 °C(lit.)