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1-Methyl-2-pyrrolidinone, biotech. grade, 2L

SKU:
494496-2L
  • $446.00

    • Description

    1-Methyl-2-pyrrolidinone

    biotech. grade, ≥99.7%

    Synonym(s):
    1-Methyl-2-pyrrolidone, N-Methyl-2-pyrrolidone, NMP
    Empirical Formula (Hill Notation):
    C5H9NO
    CAS Number:
    872-50-4
    Molecular Weight:
    99.13
    Beilstein/REAXYS Number:
    106420
    EC Number:
    212-828-1
    MDL number:
    MFCD00003193
    PubChem Substance ID:
    329757456

    PROPERTIES

    InChI key

    SECXISVLQFMRJM-UHFFFAOYSA-N

    grade

    biotech. grade

    Quality Level

    100

    vapor density

    3.4 (vs air)

    vapor pressure

    0.29 mmHg ( 20 °C)
    0.99 mmHg ( 40 °C)

    assay

    ≥99.7%

    form

    liquid

    autoignition temp.

    518 °F

    expl. lim.

    9.5 %

    impurities

    ≤0.005% water
    ≤0.01% free amines (CH3NH2)

    color

    APHA: ≤20

    refractive index

    n20/D 1.47 (lit.)

    pH

    7.7-10.0 (20 °C, 100 g/L)

    bp

    202 °C (lit.)
    81-82 °C/10 mmHg (lit.)

    mp

    −24 °C (lit.)

    solubility

    acetone: miscible(lit.)
    alcohol: miscible(lit.)
    chloroform: miscible(lit.)
    ethyl acetate: miscible(lit.)
    water: miscible(lit.)

    density

    1.028 g/mL at 25 °C (lit.)

    λ

    H2O reference

    UV absorption

    λ: 285 nm Amax: 1.00
    λ: 300 nm Amax: 0.50
    λ: 325 nm Amax: 0.10
    λ: 350-400 nm Amax: 0.01

    application(s)

    peptide synthesis

    SMILES string

    CN1CCCC1=O

    InChI

    1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3

    General description

    N-Methyl-2-pyrrolidinone (N-methylpyrrolidone, NMP) is a polar cyclic organic solvent.[1] A study on the impact of NMP on Saccharomyces cerevisiae revealed that it induced aneuploidy.[2] Characteristic properties of NMP include low viscosity, excellent dissolving power and enhanced demulsifying property. It is a better alternative to phenol in selectively treating lube feedstock.[3] The behavior of fullerene-C60 in NMP solution has been examined based on electronic absorption and photoluminescence spectral data.[1] A solution of sodium borohydride (NaBH4) in NMP showed increased reactivity towards debromination of alkyl bromide.[4] The enhanced selectivity of NMP-ethylene glycol solvent mixture for aromatic hydrocarbon extraction has been analyzed by gas chromatography.[5]

    SAFETY INFORMATION

    pictograms

    GHS07,GHS08

    signalword

    Danger

    hcodes

    H315 - H319 - H335 - H360D

    pcodes

    P202 - P261 - P264 - P302 + P352 - P305 + P351 + P338 - P308 + P313

    Hazard Classifications

    Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

    target_organs

    Respiratory system

    Storage Class

    6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

    wgk_germany

    WGK 1

    flash_point_f

    195.8 °F - Pensky-Martens closed cup

    flash_point_c

    91 °C - Pensky-Martens closed cup