1-Methyl-2-pyrrolidinone, 2L

SKU:
328634-2L
  • $303.00

    • Description

    1-Methyl-2-pyrrolidinone, 2L

    anhydrous, 99.5%

    Synonym(s):
    1-Methyl-2-pyrrolidone, N-Methyl-2-pyrrolidone, NMP
    Empirical Formula (Hill Notation):
    C5H9NO
    CAS Number:
    872-50-4
    Molecular Weight:
    99.13
    Beilstein/REAXYS Number:
    106420
    EC Number:
    212-828-1
    MDL number:
    MFCD00003193
    PubChem Substance ID:
    57648684
    NACRES:
    NA.21

    PROPERTIES

    InChI key

    SECXISVLQFMRJM-UHFFFAOYSA-N

    grade

    anhydrous

    Quality Level

    200

    vapor density

    3.4 (vs air)

    vapor pressure

    0.29 mmHg ( 20 °C)
    0.99 mmHg ( 40 °C)

    assay

    99.5%

    form

    liquid

    autoignition temp.

    518 °F

    expl. lim.

    9.5 %

    impurities

    <0.005% water

    refractive index

    n20/D 1.47 (lit.)

    pH

    7.7-10.0 (20 °C, 100 g/L)

    bp

    202 °C (lit.)
    81-82 °C/10 mmHg (lit.)

    mp

    −24 °C (lit.)

    density

    1.028 g/mL at 25 °C (lit.)

    SMILES string

    CN1CCCC1=O

    InChI

    1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3

    Application

    1-Methyl-2-pyrrolidinone may be used as a solvent in the following processes:
    • Preparation of 2-aryl and 2-alkyl benzothiazoles.[1]
    • Ullmann coupling reaction of aryl halides and phenols to form Ullmann ethers in the presence of 2,2,6,6-tetramethylheptane-3,5-dione.[2]
    • Stille cross-coupling reaction of aryl iodides with organostannanes catalyzed by Pd/C in the presence of copper iodide as cocatalyst.[3]

    Other Notes

    Pure-Pac® II containers require the Micromatic MacroValve coupler for dispensing solvents, Z560723.

    Legal Information

    Pure-Pac is a registered trademark of Merck KGaA, Darmstadt, Germany

    SAFETY INFORMATION

    pictograms

    GHS07,GHS08

    signalword

    Danger

    hcodes

    H315 - H319 - H335 - H360D

    pcodes

    P202 - P261 - P264 - P302 + P352 - P305 + P351 + P338 - P308 + P313

    Hazard Classifications

    Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

    target_organs

    Respiratory system

    Storage Class

    6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

    wgk_germany

    WGK 1

    flash_point_f

    195.8 °F - Pensky-Martens closed cup

    flash_point_c

    91 °C - Pensky-Martens closed cup

    ppe

    Eyeshields, Gloves, type ABEK (EN14387) respirator filter